Protein Alignment CG31272 and SLC22A24

DIOPT Version :9

• Sequence 1: NP_650013.3
• Gene: CG31272 / 326130
• FlyBaseID: FBgn0051272
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_001129978.2
• Gene: SLC22A24 / 283238
• HGNCID: 28542
• Length: 552
• Species: Homo sapiens
• Alignment Length: 545
• Identity: 107/545 - (19%)
• Similarity: 198/545 - (36%)
• Gaps: 133/545 - (24%)

  Fly    24 DGNSDSTAEAEATPTEEGSATFDKAIEGAGFGIFNLMLLIVSIPAQSAAIFESSSMSYILPIAEC 88
            :|...:|.|.:..|..:|             .:::....:.:|..:...:.||.|:
Human   102 NGTFPNTNEPDTEPCVDG-------------WVYDRSSFLSTIVTEWDLVCESQSL--------- 144

  Fly    89 DLRLTLEDKGVLNAVAYAGMTISAIAWGYLADTKGRK---KILYWGYLIDAVCVFGSALSQNFSM 150
                    |.::.::..||..:..:.:|:|:|..|||   |:.:....|...|   :|.:..|.:
Human   145 --------KSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCFLQLAISNTC---AAFAPTFLV 198

  Fly   151 LVMFKFLGGLVVNGPAAVLFTYLTEMHGPKHRSSVLMIVGMVTSTATVSLPLLAWGIFPRDWDFE 215
            ..:.:||.|..........|....|...|:.||..:|::....|...:.|..||:.|
Human   199 YCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCSYSVGQMLLGGLAFAI-------- 255

  Fly   216 FWGLQVHSWQIFLFVLGIPSLISGLIFCSMPESPRFLMAQGRNEEALQAFKQIYHVNTRKPKDSY 280
                  ..|.|....:..|.::..|....|.||.|:|:...:.:|.|:..:::.|:|.:|..:
Human   256 ------QDWHILQLTVSTPIIVLFLSSWKMVESARWLIINNQLDEGLKELRRVAHINGKKNTE-- 312

  Fly   281 PIKALIQEVPNRKAAQNEVIYTIEEKSGEVPTKRQSRTLAESLRAGLQQMKPLVRKPLLGLAICC 345
                        :....|::.:..:|  |:...|...::....||      |.:|..:.||   |
Human   313 ------------ETLTTELVRSTMKK--ELDAVRIKTSIFSLFRA------PKLRMRVFGL---C 354

  Fly   346 YVMQFGIFLGMNTIRLWLPQLFASMAEYEALHAGDGLDVSMCTILEFSVNQTAETALNYADACSE 410
            :| :|.|.:....:.|.|..|.::::.::.|          |..:.|:....:...||:
Human   355 FV-RFAITVPFYGLILNLQHLGSNVSLFQIL----------CGAVTFTARCVSLLTLNH------ 402

  Fly   411 PKVISMDMYLNNIIVSATGFVGYFFAGGILRALGPKRMMTYGLFLSGTFGLMLYFSVSSLMTLIV 475
                 |...::.|:.:                           |..|.|.|:..|....:..|.|
Human   403 -----MGRRISQILFT---------------------------FPVGLFILVNTFLPQEMQILRV 435

  Fly   476 SATFLTITGIAVSSLLGAV--VALFPTQLRTVVVAIAMMCGRFGALSGNLLFPVFVQTGCLP--- 535
            ....|.|..::.:|...:|  ..|.||.||:.|..|..:.||.||....||..:...:..||
Human   436 VLATLGIGSVSAASNSASVHHNELVPTILRSTVAGINAVSGRTGAALAPLLMTLMAYSPHLPWIS 500

  Fly   536 ----PFIMVSSVLILSGILSISLPD 556
                |.:.|..:|:|.....:.||:
Human   501 YGVFPILAVPVILLLPETRDLPLPN 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	100/504 (20%)
		2A0115	74..524	CDD:273327	91/454 (20%)
SLC22A24	NP_001129978.2	MFS_OAT	109..516	CDD:340932	102/527 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153598
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840