Protein Alignment CG31272 and Slc22a2

DIOPT Version :10

• Sequence 1: NP_650013.3
• Gene: CG31272 / 326130
• FlyBaseID: FBgn0051272
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_038695.1
• Gene: Slc22a2 / 20518
• MGIID: 1335072
• Length: 553
• Species: Mus musculus
• Alignment Length: 511
• Identity: 113/511 - (22%)
• Similarity: 198/511 - (38%)
• Gaps: 148/511 - (28%)

  Fly    83 LPIAECDLRLTLEDKG------------------VLNAVAYAGMTISAIAWGYLADTKGRKKILY 129
            ||::.|:.....:..|                  :..::...|..|.|:..|||||..|||..|.
Mouse   117 LPLSPCEHGWVYDTPGSSIVTEFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRKFCLL 181

  Fly   130 WGYLIDAVCVFGSALSQNFSMLVMFKFLGGLVVNGPAAVLFTYLTEMHGPKHRSSVLMIVGMVTS 194
            ...||:|:.....|:|.|::.:::|:||.|||......:.:..:||..|..:|.:    ||:...
Mouse   182 VTILINAISGVLMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRT----VGICYQ 242

  Fly   195 TA-TVSLPLLAWGIFPRDWDFEFWGLQVHSWQIFLFVLGIPSLISGLIFCSMPESPRFLMAQGRN 258
            .| ||.|.:|| |:          ...:.:|:...|.:.:|:....|.|..:|||||:|::|.:|
Mouse   243 IAFTVGLLILA-GV----------AYALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKN 296

  Fly   259 EEALQAFKQIYHVNTRKPKDSYPIKALIQEVPNRKAAQNEVIYTIEEKSGE-VPTKRQSRTLAES 322
            .:|::..|.                                   |.:|:|: ||...||.|..|.
Mouse   297 AKAMKIIKH-----------------------------------IAKKNGKSVPVSLQSLTADED 326

  Fly   323 LRAGLQQMKP----LVRKPLLGLAICCYVMQFGIFLGMNTIRLWLPQLFASMAEYEAL--H---A 378
              .|: ::.|    |||.|        .:.:..:.|..|    |    |.|...|:.|  |   |
Mouse   327 --TGM-KLNPSFLDLVRTP--------QIRKHTLILMYN----W----FTSSVLYQGLIMHMGLA 372

  Fly   379 GDG--LDVSMCTILEFSVNQTAETALNYADACSEPKVISMDMYLNNIIVSATGFVGYFFAGGILR 441
            ||.  ||.....::||                  |....:.:.::.|
Mouse   373 GDNIYLDFFYSALVEF------------------PAAFIIILTIDRI------------------ 401

  Fly   442 ALGPKRMMTYGLFLSGTFGLMLYFSVSSLMTLIVSATFLTITGIAVSSLLGAVV--ALFPTQLRT 504
              |.:........::|...|...|....|..|.::...|...||.::..:..:|  .|:||.:|.
Mouse   402 --GRRYPWAVSNMVAGAACLASVFIPDDLQWLKITVACLGRMGITIAYEMVCLVNAELYPTYIRN 464

  Fly   505 VVVAI-AMMCGRFGALSGNLLF---PVFVQTGCLPPFIMVSSVLILSGILSISLPD 556
            :.|.: :.||...|.::..|::   .::::.    |.::.:.|.:::|.|.:.||:
Mouse   465 LAVLVCSSMCDIGGIVTPFLVYRLTDIWLEF----PLVVFAVVGLVAGGLVLLLPE 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	synapt_SV2	15..556	CDD:130366	112/509 (22%)
Slc22a2	NP_038695.1	2A0119	12..525	CDD:273328	113/511 (22%)
		Proline-rich sequence. /evidence=ECO:0000250|UniProtKB:O15244	284..288		3/3 (100%)