DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31272 and Slc22a6

DIOPT Version :9

Sequence 1:	NP_650013.3	Gene:	CG31272 / 326130	FlyBaseID:	FBgn0051272	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_032792.2	Gene:	Slc22a6 / 18399	MGIID:	892001	Length:	545	Species:	Mus musculus

Alignment Length:	468	Identity:	99/468 - (21%)
Similarity:	171/468 - (36%)	Gaps:	115/468 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 GMTISAIAWGYLADTKGRKKILYWGYLIDAVCVFGSALSQNFSMLVMFKFLGGLVVNGPAAVLFT 171
            |:.:.|:.:|||||..||:|:|...||..||....:|.:.|:::..:|:.|.|:.:...|....|
Mouse   138 GVLLGAMMFGYLADRLGRRKVLILNYLQTAVSGTCAAYAPNYTVYCIFRLLSGMSLASIAINCMT 202

  Fly   172 YLTEMHGPKHRSSVLMIVGMVTSTATVSLPLLAWGIFPRDWDFEFWGLQVHSWQIFLFVLGIPSL 236
            ...|......|:.|..::|.|.|.....|..:|:.              |..|:.....:.:|..
Mouse   203 LNMEWMPIHTRAYVGTLIGYVYSLGQFLLAGIAYA--------------VPHWRHLQLAVSVPFF 253

  Fly   237 ISGLIFCSMPESPRFLMAQGRNEEALQAFKQIYHVNTRKPKDSYPIKALIQEVPNRKAAQNEVIY 301
            ::.:......||.|:..:.||.:..|:|.:::..:|.::.:.:   |..|           ||:.
Mouse   254 VAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEEGA---KLSI-----------EVLQ 304

  Fly   302 TIEEKSGEVPTKRQSRTLAESLRAGLQQMKPLVRKPLLGLAICCYVMQFGIFLGMNTIRLWLPQL 366
            |..:|.             .:|..|......|:|.|.|.....|..|            ||
Mouse   305 TSLQKE-------------LTLNKGQASAMELLRCPTLRRLFLCLSM------------LW---- 340

  Fly   367 FA-SMAEYEALHAGDGLDVSMCTILEFSVNQTAETALNYADACSEPKVISMDMYLNNIIVSATGF 430
            || |.|.|..:....|..||                                |||..:|..|...
Mouse   341 FATSFAYYGLVMDLQGFGVS--------------------------------MYLIQVIFGAVDL 373

  Fly   431 VGYFFAGGILRALGPKRMMTYGLFLSGTFGLMLYFSVSSLM----TLIVSATFLTITGIAVSS-- 489
            ...|....::.::|.:......|.|:|     :...|:.::    |:|.::..:...|...||
Mouse   374 PAKFVCFLVINSMGRRPAQLASLLLAG-----ICILVNGIIPRGHTIIRTSLAVLGKGCLASSFN 433

  Fly   490 -LLGAVVALFPTQLRTVVVAIAMMCGRFGALSGNLL---------FPVFVQTGCLPPFIMVSSV- 543
             :......|:||.:|...:.:.....|.|::...|:         .|:|: .|.:|  :..|:|
Mouse   434 CIFLYTGELYPTMIRQTGLGMGSTMARVGSIVSPLISMTAEFYPSIPLFI-FGAVP--VAASAVT 495

  Fly   544 LILSGILSISLPD 556
            .:|...|...|||
Mouse   496 ALLPETLGQPLPD 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31272	NP_650013.3	MFS	62..555	CDD:119392	96/465 (21%)
CG31272	NP_650013.3	2A0115	74..524	CDD:273327	87/424 (21%)
Slc22a6	NP_032792.2	2A0119	11..509	CDD:273328	99/468 (21%)
		MFS	129..499	CDD:119392	94/457 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	515..545
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843760
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930