DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hang and CG2129

DIOPT Version :9

Sequence 1:	NP_001138204.1	Gene:	hang / 32613	FlyBaseID:	FBgn0026575	Length:	2223	Species:	Drosophila melanogaster
Sequence 2:	NP_572449.1	Gene:	CG2129 / 31741	FlyBaseID:	FBgn0030008	Length:	465	Species:	Drosophila melanogaster

Alignment Length:	640	Identity:	118/640 - (18%)
Similarity:	180/640 - (28%)	Gaps:	276/640 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly  1274 RMRCRICQRRFSSKKSYRYHMLTDHQVQNVQF----IKCKLCNA--------------------- 1313
            |:.|..|:     .||:.:.....| |||:.|    :|.:..:|
  Fly    30 RIDCAFCE-----MKSFVFGDFLLH-VQNIHFENGLLKTEATDAGANLKQERDREREPNSPVPIV 88

  Fly  1314 ----EFA-YEKGLKVHLFKVHGKAIKDEMIIKQFECDVCSIVYSSESELQQHKRSVHKLTSASAS 1373
                .|| ||.|      ..|.:...||.::.:.:         .|.|.::..||:.|.....:.
  Fly    89 AQVNPFAWYEIG------GDHNEDSDDERVVLEKQ---------DEDEDERPGRSIIKWQDHQSL 138

  Fly  1374 TSAS----TSSKID---DDSLMDD-GKPTSSDLADLSTLAAGGSTASAPLYWYQCKYCPSNFNTN 1430
            ||.|    .:.|:|   :||..:: |.....|       :.|..:|..|   :.|.:|...:.:.
  Fly   139 TSESLRQVRALKVDYKEEDSEQEECGMELDLD-------SEGRHSAKIP---HSCPHCTKVYQSR 193

  Fly  1431 KKLAIHI-NSH-----DEFDSND-----------------YSCKDCGNVYSGRKSLWVHRYKKHP 1472
            |.|..|| ..|     .:.||.|                 |.|:.||.:|.|:.||..|..:.|
  Fly   194 KVLERHIMRQHKDTLSPDVDSEDADYEPPKDAPVKSAAQEYKCEHCGKIYHGKYSLRQHLKRDH- 257

  Fly  1473 QVPNPAE-------CSLCRKVFFDRQMHDNHTPTCNRKPITSTGAHQQQDGQLHSHHTAKRTIFR 1530
              .|..|       |..|.......::.|.|                    .:.:|..|
  Fly   258 --DNGEEGGSAIFTCLECEAQLPRLRLLDEH--------------------MVQAHGGA------ 294

  Fly  1531 HKTGDDDDEEDDDEQQQLEERANSDGNGTTVGVASGSTAAAGTSLKIRIPEVACTICGARFTDQE 1595
                                                                ||.:||.|:..:.
  Fly   295 ----------------------------------------------------ACVVCGRRYKTRH 307

  Fly  1596 HFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKW 1660
            ...:|..||..|..|..|...                           |.|.|..:..::.|.|.
  Fly   308 ELKRHQLKHTSERNVPCPHPG---------------------------CGKRFFTIRHMRNHGKV 345

  Fly  1661 HFRGDSKQNPIDGEATQLTNNNHTTNNNNNNSMHLRELHAVGLMPNQQQQSLNNSCNSSMNHNNN 1725
            |                                            .:|:..:..||..|. .|..
  Fly   346 H--------------------------------------------TEQKNFVCESCGYSC-RNKE 365

  Fly  1726 SSSNRSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIVVDDHLTCRRCQLK 1790
            :.....:|...:|...|:.|...|.|::.||.|| .:|..|     .|.|        |..|...
  Fly   366 TLRVHIRSHTGERPFGCQVCDKRFPSHSGLREHM-AMHSTE-----RPHV--------CSVCGAT 416

  Fly  1791 FDTKELWIEHKL--ADAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEEV 1843
            |..::....||.  ||.|        |:.|.|||...::...|..|:..|..:|:
  Fly   417 FSRQKGLYHHKFLHADTK--------QFVCKLCGNAYAQAAGLAGHMRKHRNDEL 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hang	NP_001138204.1	zf-AD	80..154	CDD:285071
		C2H2 Zn finger	1036..1057	CDD:275368
		C2H2 Zn finger	1067..1088	CDD:275368
		C2H2 Zn finger	1279..1298	CDD:275371	3/18 (17%)
		C2H2 Zn finger	1308..1325	CDD:275371	6/42 (14%)
		C2H2 Zn finger	1420..1440	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1450..1468	CDD:275368	8/17 (47%)
CG2129	NP_572449.1	C2H2 Zn finger	296..316	CDD:275370	5/19 (26%)
		zf-C2H2_8	323..411	CDD:292531	26/173 (15%)
		C2H2 Zn finger	327..346	CDD:275368	5/45 (11%)
		C2H2 Zn finger	354..374	CDD:275368	4/20 (20%)
		zf-H2C2_2	367..389	CDD:290200	4/21 (19%)
		C2H2 Zn finger	382..402	CDD:275368	8/20 (40%)
		zf-H2C2_2	395..419	CDD:290200	11/37 (30%)
		C2H2 Zn finger	410..430	CDD:275368	5/19 (26%)
		C2H2 Zn finger	438..458	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440027
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930