DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31223 and Znhit2

DIOPT Version :9

Sequence 1:	NP_732563.2	Gene:	CG31223 / 326127	FlyBaseID:	FBgn0051223	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_001101044.1	Gene:	Znhit2 / 309177	RGDID:	1307918	Length:	400	Species:	Rattus norvegicus

Alignment Length:	427	Identity:	94/427 - (22%)
Similarity:	165/427 - (38%)	Gaps:	127/427 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CHFC---REVSFKYTCPKCNALYCSVGCYKSKEHLKCSEAFYKSCIQDELTQNTVTQESQEDMRK 69
            |.||   ..|..:||||:|||.|||:.||::  |..|:|.||:..:..||.....:..      :
  Rat     7 CGFCPAGEAVPARYTCPRCNAPYCSLRCYRA--HGACAEDFYRDQVLRELRGRNASPS------R 63

  Fly    70 IYDILKRMRETDSGFNPQEFDTDGLENSLDSDGGEEGESEEDEAEENVTEGDILDEDLEEDIATR 134
            :...|:|:|                         |:.|:|::..|..:..|            ||
  Rat    64 LAGALRRLR-------------------------EQREAEDEPEETGLRPG------------TR 91

  Fly   135 LKGVDINDADEVWSRLTTEEQDEFQKLITNGDIMKLMPDYKPWW--------------------- 178
            ..|:     ..:|.||...|:..|::|::.|:..:|:|.::|||
  Rat    92 PGGL-----SGLWERLAPAEKAAFERLLSRGEAGRLLPPWRPWWWGRGTGPRFLEELDDDASRDL 151

  Fly   179 ----IKPKNSKIVII--------PTPEEAAKKESRVPEIFGSIAKFSDICKKTPSPCLHYNLWNI 231
                :.|..:.:..:        |..|:::  .:|.|.:...|...:.:.:...||.:.:.|.|:
  Rat   152 AEPELLPARTGLESVDDAAAAGEPLAEDSS--VARPPAMPARIPALASLSRSPTSPLVRFQLPNV 214

  Fly   232 LSAYA-CVARFFGGEQRTNASEAVAHLVNLSATLKYGTNFEDAEDAIVSVEMEAITTGNGPAGAA 295
            |.||| .:|.:.||:.....|:..|.|:::|..|.....|...|:|: ......:..|..|.|.
  Rat   215 LFAYAHTLALYHGGDDDALLSDFCATLLDVSGALGTQQVFHSTEEAL-QAAAHVLEAGEHPPGP- 277

  Fly   296 AVGSAAGGANFLVDNREQLQQDARQLMA-----TKEHKLAALSDVLYLLQQTKAISRRKNTQEAE 355
                        :..|..:|:.||.|:.     .|.:.|.||..    |.||...:|::
  Rat   278 ------------LGTRGAMQEVARILLGEGPINQKGYTLIALGH----LAQTLGRARKQ------ 320

  Fly   356 FQKLFALASGSVQLDRTKLAQLVRKIEFMLSYVAREE 392
                     ..|..:|.:|.:..:|.:|:|::....|
  Rat   321 ---------AVVGEERDRLYRARKKCQFLLAWTNENE 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31223	NP_732563.2	zf-HIT	6..34	CDD:398237	15/28 (54%)
Znhit2	NP_001101044.1	zf-HIT	3..36	CDD:282314	15/28 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353094
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8477
Inparanoid	1	1.050	82	1.000	Inparanoid score	I5104
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1599898at2759
OrthoFinder	1	1.000	-	-		FOG0004684
OrthoInspector	1	1.000	-	-		oto98112
orthoMCL	1	0.900	-	-		OOG6_103585
Panther	1	1.100	-	-	LDO	PTHR15555
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3291
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.900