DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rumi and poglut3

DIOPT Version :9

Sequence 1:	NP_651095.1	Gene:	rumi / 326122	FlyBaseID:	FBgn0086253	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001092215.1	Gene:	poglut3 / 566063	ZFINID:	ZDB-GENE-060810-142	Length:	518	Species:	Danio rerio

Alignment Length:	378	Identity:	104/378 - (27%)
Similarity:	164/378 - (43%)	Gaps:	61/378 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 DPQDSDCSCHANVLKRDLAPYKSTGVTRQMIESSARYGTK-----YKIYGHRLYRDANCMFPARC 126
            |||          :::|.:.:.|..:.:.:.|...|:..:     |.|..::::|.:...:....
Zfish   169 DPQ----------IQKDFSSFPSIDLQQLLQEVPTRFAKRGGLIHYTILNNQVHRRSLGRYTDFK 223

  Fly   127 EGIEHFLLPLV--ATLPDMDLIINTRDYPQLNAAWGNAAGG-PVFSFSKTKEYRDIMYPAWTFWA 188
            ...:..||.|.  ..|||::..||..|:|..|....:..|. ||.|:..:.|.|||:.|.:..
Zfish   224 MFSDEILLSLARKVKLPDVEFYINVGDWPMENRKVNDNPGPVPVISWCGSTETRDIILPTYDI-- 286

  Fly   189 GGPATKLHP-----RGIGRWDQMREKLEKRAAAIP-WSQKRSLGFFRGSRTSDERDSLILLSRRN 247
                  .|.     ||:     ..:.|..:....| ||.|.:..||||..:.:||..|:.:|:.|
Zfish   287 ------THSSLEAMRGV-----TNDLLSVQGNTGPTWSDKMNKAFFRGRDSREERLRLVTMSKEN 340

  Fly   248 PELVEAQYTKNQGWKS-PKDTLDAPAADEVSFEDHCKYKYLFNFRGVAASFRLKHLFLCKSLVFH 311
            |||::|..|....::. .||...||.   |.|.|..||||..|..|..|::|..:|.|..|||..
Zfish   341 PELLDAGITAYFFFRDREKDLGKAPL---VGFFDFFKYKYQVNVDGTVAAYRFPYLMLGNSLVLK 402

  Fly   312 VGDEWQEFFYDQLKPWVHYVPLKSYPSQQEYEHILSFFKKNDALAQEIAQRGYDFIWEHLRMKDI 376
            ....:.|.||..|||.|||:|:|.  ...:....:.:.|.||..|:.||:||...:.:.|:...:
Zfish   403 QDSPYYEHFYTHLKPGVHYIPVKR--DLSDLIEKIKWAKSNDTEAEAIARRGQSLVRDLLQPHRL 465

  Fly   377 KCYWRKLLKRYVKL----------LQYEVKPEDQLIYIG--------PKKDEL 411
            .||:.|:.:.|...          ::...:|.||.....        |:||||
Zfish   466 YCYYYKVFQTYADRQSSRPAVHPDMEIVPQPTDQTALCNCKRAENQKPQKDEL 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rumi	NP_651095.1	CAP10	139..394	CDD:214773	83/272 (31%)
poglut3	NP_001092215.1	Filamin	38..139	CDD:279024
		IG_FLMN	39..141	CDD:214720
		Glyco_transf_90	160..495	CDD:304992	96/353 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2458
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810