Protein Alignment HDAC11 and HOS2

DIOPT Version :9

• Sequence 1: NP_001247296.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: NP_011321.1
• Gene: HOS2 / 852681
• SGDID: S000003162
• Length: 452
• Species: Saccharomyces cerevisiae
• Alignment Length: 330
• Identity: 80/330 - (24%)
• Similarity: 129/330 - (39%)
• Gaps: 66/330 - (20%)

  Fly    44 FGGLERLHPFDAAKGKH------IHKLLCAQLQLDDGSFYEPTELTKDQLRRIHTREYLKSL--- 99
            :|....:.||......|      :||::         ..||....|:|:|.:.|:.:|:..|
Yeast    41 YGVKHPMKPFRLMLTDHLVSSYGLHKIM---------DLYETRSATRDELLQFHSEDYVNFLSKV 96

  Fly   100 ---------RWSM-NVACIAEVPLMAFVPNRYIQRSYLRPMRFQAAGSILAGKLALDYGWAINLG 154
                     |.:: |.....:.|:.   .|.|...:........|...::..:..:    |||..
Yeast    97 SPENANKLPRGTLENFNIGDDCPIF---QNLYDYTTLYTGASLDATRKLINNQSDI----AINWS 154

  Fly   155 GGFHHCCSYRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQGNGHERDFNNVAAVYI-- 217
            ||.||.......|||...||.|.|:.|....|    ||:.:|:|.|.|:|.:..|.....|:.
Yeast   155 GGLHHAKKNSPSGFCYVNDIVLSILNLLRYHP----RILYIDIDLHHGDGVQEAFYTTDRVFTLS 215

  Fly   218 FDMYNAFVYPRDHVAKESIRC--------AVELRNYTEDGFYLRQLKRCLMQSLAEFRPDMVVYN 274
            |..||...:|......| |.|        .|.|.:..:|..|:...|..:...:..|:|.::|..
Yeast   216 FHKYNGEFFPGTGDLTE-IGCDKGKHFALNVPLEDGIDDDSYINLFKSIVDPLIMTFKPTLIVQQ 279

  Fly   275 AGTDVLEGDPLG--NLAISAEGVIERDRLVFSTFRALGIPVVMLLSGGYLKAS--------AGVI 329
            .|.|.|..|.||  ||.|.|.|  |..:.|    ::.|:|::::..|||...:        .|::
Yeast   280 CGADSLGHDRLGCFNLNIKAHG--ECVKFV----KSFGLPMLVVGGGGYTPRNVSRLWTYETGIL 338

  Fly   330 TDSIV 334
            .|.::
Yeast   339 NDVLL 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_001247296.1	HDAC_classIV	51..336	CDD:212519	79/323 (24%)
HOS2	NP_011321.1	HDAC_Hos2	28..338	CDD:212540	79/323 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810