Protein Alignment HDAC11 and Hdac5

DIOPT Version :9

• Sequence 1: NP_001247296.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: XP_038942911.1
• Gene: Hdac5 / 84580
• RGDID: 619980
• Length: 1120
• Species: Rattus norvegicus
• Alignment Length: 483
• Identity: 97/483 - (20%)
• Similarity: 162/483 - (33%)
• Gaps: 186/483 - (38%)

  Fly     6 ERVHHEEQESEEVVWVKRDDARSA---GKLPIVFSRNYAVRFGGLERLHPFD------------- 54
            |....||::.|:.:.||.:|..|.   |......|..|...|...::|.|..
  Rat   597 EEEEDEEEDEEDCIQVKDEDGESGPDEGADLEESSAGYKKLFADAQQLQPLQVYQAPLSLATVPH 661

  Fly    55 ----------AAKG------------KHI-------------HKLLCAQL--------------- 69
                      ||.|            ||:             |:.:|...
  Rat   662 QALGRTQSSPAAPGSMKSPTDHPTVVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWS 726

  Fly    70 QLDDGSFYEPTE------LTKDQLRRIHT-------------REYLKSLR--------------- 100
            :|.:.......|      .|.|:::.:|:             |:.|.|.:
  Rat   727 RLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAMLPC 791

  Fly   101 ----------WS---------MNVACIAEVPLMAFVPNRYIQRSYLRPMRFQAAGSILAGKLALD 146
                      |:         |.|.|:.|   :||                    .:.||:  |.
  Rat   792 GGIGVDSDTVWNEMHSSSAVRMAVGCLVE---LAF--------------------KVAAGE--LK 831

  Fly   147 YGWAINLGGGFHHCCSYRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQGNGHERDFNN 211
            .|:||....| ||.......|||.:..:::....|  |:...|.:::|||.|.|.|||.::.|.:
  Rat   832 NGFAIIRPPG-HHAEESTAMGFCFFNSVAITAKLL--QQKLSVGKVLIVDWDIHHGNGTQQAFYD 893

  Fly   212 VAAVYIFDMY---NAFVYPRDHVAKE---------SIRCAVELRNYT-------EDGFYLRQLKR 257
            ..:|....::   |...:|.....:|         ::..|     :|       .|..||...:.
  Rat   894 DPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVA-----WTGGVDPPIGDVEYLTAFRT 953

  Fly   258 CLMQSLAEFRPDMVVYNAGTDVLEG--DPLGNLAISAE--GVIERDRLVFSTFRALGIPVVMLLS 318
            .:|....||.||:|:.:||.|.:||  .|||..:::|.  |.:.|..:..:     |..||:.|.
  Rat   954 VVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLA-----GGRVVLALE 1013

  Fly   319 GGY-----LKASAGVITDSIVNLRLQGL 341
            ||:     ..||...:: :::::.||.|
  Rat  1014 GGHDLTAICDASEACVS-ALLSVELQPL 1040

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_001247296.1	HDAC_classIV	51..336	CDD:212519	81/428 (19%)
Hdac5	XP_038942911.1	ClassIIa_HDAC_Gln-rich-N	87..174	CDD:421006
		Arginase_HDAC	689..1105	CDD:418394	79/391 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900