Protein Alignment HDAC11 and Hdac1l

DIOPT Version :10

• Sequence 1: NP_733048.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: NP_445898.1
• Gene: Hdac1l / 84576
• RGDID: 619975
• Length: 484
• Species: Rattus norvegicus
• Alignment Length: 302
• Identity: 75/302 - (24%)
• Similarity: 125/302 - (41%)
• Gaps: 55/302 - (18%)

  Fly    51 HPFDAAKGKHIHKLLCAQLQLDDGSF-----YEPTELTKDQLRRIHTREYLKSLRWSMNVACIAE 110
            ||....:.:..|.||     |:.|.:     |.|.:...:::.:.|:.:|:|.|| |:....::|
  Rat    28 HPMKPHRIRMTHNLL-----LNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLR-SIRPDNMSE 86

  Fly   111 VPLMAFVPNRYIQR-----------SYLRPMRFQAAGSILA----GKLALDYGWAINLGGGFHHC 160
            .       ::.:||           ......:....||:.:    .|...|.  |:|..||.|:.
  Rat    87 Y-------SKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDI--AVNWAGGLHYA 142

  Fly   161 CSYRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQGNGH--ERDFNNVAAVYI--FDMY 221
            ......|||...||.|.|:.|.:..    :|::.:|:|.|.|:|.  |..|.....|..  |..|
  Rat   143 KKSEASGFCYVNDIVLAILELLKYH----QRVLYIDIDIHHGDGDGVEEAFYTTDRVMTVSFHKY 203

  Fly   222 NAFVYP-----RDHVAKESIRCAVE--LRNYTEDGFYLRQLKRCLMQSLAEFRPDMVVYNAGTDV 279
            ..: :|     ||..|.:....||.  ||:..:|..|....|..:.:.:..|:|..||...|:|.
  Rat   204 GEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDS 267

  Fly   280 LEGDPLGNLAISAEGVIERDRLVFSTFRALGIPVVMLLSGGY 321
            |.||.||...::.:|..:....|    ::..:|::||...||
  Rat   268 LSGDRLGCFNLTIKGHAKCVEFV----KSFNLPMLMLGGDGY 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_733048.1	HDAC_classIV	51..336	CDD:212519	75/302 (25%)
Hdac1l	NP_445898.1	Arginase_HDAC	4..376	CDD:450134	75/302 (25%)