Protein Alignment HDAC11 and Hdac8

DIOPT Version :9

• Sequence 1: NP_001247296.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: XP_006528338.1
• Gene: Hdac8 / 70315
• MGIID: 1917565
• Length: 386
• Species: Mus musculus
• Alignment Length: 342
• Identity: 74/342 - (21%)
• Similarity: 129/342 - (37%)
• Gaps: 61/342 - (17%)

  Fly    24 DDARSAGKLP--IVFSRNYAVRFGGLERLHPFDAAKGKHIHKLLCAQLQLDDGSFYEPTELTKDQ 86
            :.|.|...||  .::|..|......|.::    ..:...:|.|:.|..........:|...:.::
Mouse     6 EPANSGHSLPPVYIYSPEYVSICDSLVKV----PKRASMVHSLIEAYALHKQMRIVKPKVASMEE 66

  Fly    87 LRRIHTREYLK---------------SLRWSMNVACIAEVPLMAFVPNRYIQRSYLRPMRFQAAG 136
            :...||..||:               |:.:.:...|.|...:..:.       :.:......||.
Mouse    67 MATFHTDAYLQHLQKVSQEGDEDHPDSIEYGLGYDCPATEGIFDYA-------AAIGGGTITAAQ 124

  Fly   137 SILAGKLALDYGWAINLGGGFHHCCSYRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQ 201
            .::.||..:    |||..||:||.......|||...|..|.|:||..    :..||:.||||.|.
Mouse   125 CLIDGKCKV----AINWSGGWHHAKKDEASGFCYLNDAVLGILRLRR----KFDRILYVDLDLHH 181

  Fly   202 GNGHERDFNNVAAVYIFDM--YNAFVYPRDHVAKE---------SIRCAVELRNYTEDGFYLRQL 255
            |:|.|..|:..:.|....:  ::...:|......:         |:.  |.:::..:|..|....
Mouse   182 GDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDMSDVGLGKGRYYSVN--VPIQDGIQDEKYYHIC 244

  Fly   256 KRCLMQSLAEFRPDMVVYNAGTDVLEGDPLGNLAISAEGVIERDRLVFSTFRALGIPVVMLLSGG 320
            :..|.:....|.|..||...|.|.:.|||:.:..::..|:.:..:.|..    ..:..::|..||
Mouse   245 ESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYVLQ----WQLATLILGGGG 305

  Fly   321 YLKAS--------AGVI 329
            |..|:        .|||
Mouse   306 YNLANTARCWTYLTGVI 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_001247296.1	HDAC_classIV	51..336	CDD:212519	67/313 (21%)
Hdac8	XP_006528338.1	HDAC8	16..370	CDD:212524	70/332 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810