Protein Alignment HDAC11 and HDAC1

DIOPT Version :10

• Sequence 1: NP_733048.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: NP_647918.2
• Gene: HDAC1 / 38565
• FlyBaseID: FBgn0015805
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 303
• Identity: 84/303 - (27%)
• Similarity: 128/303 - (42%)
• Gaps: 59/303 - (19%)

  Fly    51 HPFDAAKGKHIHKLLCAQLQLDDGSF-----YEPTELTKDQLRRIHTREYLKSLRWSMNVACIAE 110
            ||....:.:..|.||     |:.|.:     |.|.:.|.|::.:.|:.||::.|| |:....::|
  Fly    26 HPMKPHRIRMTHNLL-----LNYGLYRKMEIYRPHKATADEMTKFHSDEYVRFLR-SIRPDNMSE 84

  Fly   111 VPLMAFVPNRYIQRSYLR---PM--------RFQAAGSILA----GKLALDYGWAINLGGGFHHC 160
            .       |:.:||..:.   |:        :..|.||:.|    .|.|.:.  .||.|||.||.
  Fly    85 Y-------NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEI--CINWGGGLHHA 140

  Fly   161 CSYRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQGNGHERDFNNVAAVYI--FDMYNA 223
            ......|||...||.|.|:.|.:..    :|::.:|:|.|.|:|.|..|.....|..  |..|..
  Fly   141 KKSEASGFCYVNDIVLGILELLKYH----QRVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKYGE 201

  Fly   224 FVYP-----RDHVAKESIRCAVE--LRNYTEDGFYLRQLKRCLMQSLAEFRPDMVVYNAGTDVLE 281
            : :|     ||..|.:....||.  ||:..:|..|.......:.:.:..|:|..||...|.|.|.
  Fly   202 Y-FPGTGDLRDIGAGKGKYYAVNIPLRDGMDDDAYESIFVPIISKVMETFQPAAVVLQCGADSLT 265

  Fly   282 GDPLG--NLAISAEG-VIERDRLVFSTFRALGIPVVMLLSGGY 321
            ||.||  ||.:...| .:|       ..:...:|.:|:..|||
  Fly   266 GDRLGCFNLTVKGHGKCVE-------FVKKYNLPFLMVGGGGY 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_733048.1	HDAC_classIV	51..336	CDD:212519	84/303 (28%)
HDAC1	NP_647918.2	Arginase_HDAC	5..372	CDD:450134	84/303 (28%)