Protein Alignment HDAC11 and Hdac8

DIOPT Version :10

• Sequence 1: NP_733048.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: XP_017457598.1
• Gene: Hdac8 / 363481
• RGDID: 1562895
• Length: 393
• Species: Rattus norvegicus
• Alignment Length: 345
• Identity: 74/345 - (21%)
• Similarity: 130/345 - (37%)
• Gaps: 61/345 - (17%)

  Fly    21 VKRDDARSAGKLP--IVFSRNYAVRFGGLERLHPFDAAKGKHIHKLLCAQLQLDDGSFYEPTELT 83
            :..:.|.|...||  .::|..|......|.::    ..:...:|.|:.|..........:|...:
  Rat     3 IPEEPANSGHSLPPVYIYSPEYVSICDSLVKV----PKRASMVHSLIEAYALHKQMRIVKPKVAS 63

  Fly    84 KDQLRRIHTREYLK---------------SLRWSMNVACIAEVPLMAFVPNRYIQRSYLRPMRFQ 133
            .:::...||..||:               |:.:.:...|.|...:..:.       :.:......
  Rat    64 MEEMATFHTDAYLQHLQKVSQEGDEDHPDSIEYGLGYDCPATEGIFDYA-------AAIGGGTIT 121

  Fly   134 AAGSILAGKLALDYGWAINLGGGFHHCCSYRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLD 198
            ||..::.||..:    |||..||:||.......|||...|..|.|:||..    :..||:.||||
  Rat   122 AAQCLIDGKCKV----AINWSGGWHHAKKDEASGFCYLNDAVLGILRLRR----KFDRILYVDLD 178

  Fly   199 AHQGNGHERDFNNVAAVYIFDM--YNAFVYPRDHVAKE---------SIRCAVELRNYTEDGFYL 252
            .|.|:|.|..|:..:.|....:  ::...:|......:         |:.  |.:::..:|..|.
  Rat   179 LHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDMSDVGLGKGRYYSVN--VPIQDGIQDEKYY 241

  Fly   253 RQLKRCLMQSLAEFRPDMVVYNAGTDVLEGDPLGNLAISAEGVIERDRLVFSTFRALGIPVVMLL 317
            ...:..|.:....|.|..||...|.|.:.|||:.:..::..|:.:..:.|..    ..:..::|.
  Rat   242 HICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYVLQ----WQLATLILG 302

  Fly   318 SGGYLKAS--------AGVI 329
            .|||..|:        .|||
  Rat   303 GGGYNLANTARCWTYLTGVI 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_733048.1	HDAC_classIV	51..336	CDD:212519	67/313 (21%)
Hdac8	XP_017457598.1	HDAC8	16..335	CDD:212524	70/332 (21%)