Protein Alignment HDAC11 and Hdac4

DIOPT Version :10

• Sequence 1: NP_733048.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: XP_017452030.3
• Gene: Hdac4 / 363287
• RGDID: 619979
• Length: 1101
• Species: Rattus norvegicus
• Alignment Length: 363
• Identity: 77/363 - (21%)
• Similarity: 129/363 - (35%)
• Gaps: 111/363 - (30%)

  Fly     9 HHEEQESEEVVWVKRDDARSAGKLPIVFSRNYAVRFGGLERLHPFDAAKGKHIHKLLCAQLQLDD 73
            |.|.....:.:|.:..:....||...:..|...:.  .|:.:|       ...|.||
  Rat   692 HPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLE--ELQTVH-------SEAHTLL-------- 739

  Fly    74 GSFYEPTELTKDQLRRIHTREYLKSLR------------------WS---------MNVACIAEV 111
               |....|.:   :::.:::.|.||.                  |:         :.|.|:.|
  Rat   740 ---YGTNPLNR---QKLDSKKLLGSLTSVFVRLPCGGVGVDSDTIWNEVHSSGAARLAVGCVVE- 797

  Fly   112 PLMAFVPNRYIQRSYLRPMRFQAAGSILAGKLA---LDYGWAINLGGGFHHCCSYRGGGFCPYAD 173
                                       |..|:|   |..|:|:....| ||.......|||.:..
  Rat   798 ---------------------------LVFKVATGELKNGFAVVRPPG-HHAEESTPMGFCYFNS 834

  Fly   174 ISLLIVRLFEQEPFRVRRIMIVDLDAHQGNGHERDFNN-----VAAVYIFDMYNAFVYPRDHVAK 233
            :::....|  |:...|.:|:|||.|.|.|||.::.|.|     ..:::.:|..|.|  |......
  Rat   835 VAIAAKLL--QQRLNVSKILIVDWDVHHGNGTQQAFYNDPNVLYMSLHRYDDGNFF--PGSGAPD 895

  Fly   234 E---------SIRCAVE--LRNYTEDGFYLRQLKRCLMQSLAEFRPDMVVYNAGTDVLEG--DPL 285
            |         ::..|..  |.....|..||...:..:|....||.||:|:.::|.|.:||  .||
  Rat   896 EVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIANEFAPDVVLVSSGFDAVEGHPTPL 960

  Fly   286 GNLAISAE--GVIERDRLVFSTFRALGIPVVMLLSGGY 321
            |...:||:  |.:.:..:..:     |..:|:.|.||:
  Rat   961 GGYNLSAKCFGYLTKQLMGLA-----GGRIVLALEGGH 993

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_733048.1	HDAC_classIV	51..336	CDD:212519	70/321 (22%)
Hdac4	XP_017452030.3	None