Protein Alignment HDAC11 and Hdac10

DIOPT Version :9

• Sequence 1: NP_001247296.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: XP_006242280.1
• Gene: Hdac10 / 362981
• RGDID: 1305874
• Length: 666
• Species: Rattus norvegicus
• Alignment Length: 352
• Identity: 77/352 - (21%)
• Similarity: 135/352 - (38%)
• Gaps: 84/352 - (23%)

  Fly     5 TERVHHEEQESEEVVWVKRDDARSAGKLPIVFSRNYAVRFGGLERL-HPFDAAKGKHIHKLLCAQ 68
            |..|:||:..:..::|   ||.....:.|              ||| ...|..:.:.:.: .|..
  Rat     3 TALVYHEDMTATRLLW---DDPECEIECP--------------ERLTAALDGLRQRGLEE-RCQC 49

  Fly    69 LQLDDGSFYEPTELTKDQLRRIHTREYLKSLRWSMNVACIAEVPLMAFVPNRYIQRSYLRPMRFQ 133
            |.:        .|.::::|..:|:.||:..::.:..:    :...:..:..:| ...|..|..|.
  Rat    50 LSV--------CEASEEELGLVHSPEYIALVQKTQTL----DKEELHTLSKQY-DAVYFHPDTFH 101

  Fly   134 ----AAG-------SILAGKLALDYGWAINLGGGFHHCCSYRGGGFCPYADISLLIVRLFEQEPF 187
                |||       ::|.|  |:..|.|:....| ||.......|||.:.:::  |.....::.:
  Rat   102 CARLAAGAALRLVDAVLTG--AVHNGVALVRPPG-HHSQRAAANGFCVFNNVA--IAARHAKQKY 161

  Fly   188 RVRRIMIVDLDAHQGNGHERDFNNVAAVYIFDMYN-------AFVYPRDHVAKESIRCAVELRNY 245
            .::||:|||.|.|.|.|.:..|.:..:|..|..:.       .|:...|         |..:...
  Rat   162 GLQRILIVDWDVHHGQGIQYIFEDDPSVLYFSWHRYEHGNFWPFLPESD---------ADTVGRG 217

  Fly   246 TEDGF---------------YLRQLKRCLMQSLAEFRPDMVVYNAGTDVLEGDPLGNLAISAEGV 295
            ...||               ||......|:....||.|::|:.:||.|...|||.|.:..:.|..
  Rat   218 RGQGFTVNLPWNQVGMGNADYLAAFLHVLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECF 282

  Fly   296 IERDRLVFSTFRAL-GIPVVMLLSGGY 321
            ....:|:    :.| |..:..:|.|||
  Rat   283 AHLTQLL----QVLAGGRICAVLEGGY 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_001247296.1	HDAC_classIV	51..336	CDD:212519	66/305 (22%)
Hdac10	XP_006242280.1	Arginase_HDAC	18..354	CDD:302587	73/337 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900