Protein Alignment HDAC11 and Hdac11

DIOPT Version :9

• Sequence 1: NP_001247296.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: NP_659168.1
• Gene: Hdac11 / 232232
• MGIID: 2385252
• Length: 347
• Species: Mus musculus
• Alignment Length: 310
• Identity: 167/310 - (53%)
• Similarity: 212/310 - (68%)
• Gaps: 1/310 - (0%)

  Fly    33 PIVFSRNYAVRFGGLERLHPFDAAKGKHIHKLLCAQLQLDDGSFYEPTELTKDQLRRIHTREYLK 97
            |||:|..|.:.|.|||:||||||.|...:...|..:..|.||...|..|.:::.|..:|||.||.
Mouse    17 PIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDGMLVEAREASEEDLLVVHTRRYLN 81

  Fly    98 SLRWSMNVACIAEVPLMAFVPNRYIQRSYLRPMRFQAAGSILAGKLALDYGWAINLGGGFHHCCS 162
            .|:||..||.|.|:|.:.|:||..:||..|||:|.|..|:|:|||||::.|||||:|||||||.|
Mouse    82 ELKWSFVVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSS 146

  Fly   163 YRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQGNGHERDFNNVAAVYIFDMYNAFVYP 227
            .||||||.||||:|.|..|||:.. .:.|..|:||||||||||||||.....|||.|:||..:||
Mouse   147 DRGGGFCAYADITLAIKFLFERVE-GISRATIIDLDAHQGNGHERDFMGDKRVYIMDVYNRHIYP 210

  Fly   228 RDHVAKESIRCAVELRNYTEDGFYLRQLKRCLMQSLAEFRPDMVVYNAGTDVLEGDPLGNLAISA 292
            .|..|||:||..|||...|||..||.:::|.:.:||.|..||:|||||||||||||.||.|:||.
Mouse   211 GDRFAKEAIRRKVELEWGTEDEEYLEKVERNVRRSLQEHLPDVVVYNAGTDVLEGDRLGGLSISP 275

  Fly   293 EGVIERDRLVFSTFRALGIPVVMLLSGGYLKASAGVITDSIVNLRLQGLL 342
            .|:::||.:||...||..||::|:.||||.|.:|.:|.|||:||...||:
Mouse   276 AGIVKRDEVVFRVVRAHDIPILMVTSGGYQKRTARIIADSILNLHDLGLI 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_001247296.1	HDAC_classIV	51..336	CDD:212519	153/284 (54%)
Hdac11	NP_659168.1	Histone deacetylase	14..318		163/301 (54%)
		HDAC_classIV	35..319	CDD:212519	153/284 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849188
Domainoid	1	1.000	295	1.000	Domainoid score	I1481
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11743
Inparanoid	1	1.050	326	1.000	Inparanoid score	I2462
Isobase	1	0.950	-	0	Normalized mean entropy	S2192
OMA	1	1.010	-	-		QHG57761
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006007
OrthoInspector	1	1.000	-	-		oto93545
orthoMCL	1	0.900	-	-		OOG6_103672
Panther	1	1.100	-	-	LDO	PTHR48252
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3706
SonicParanoid	1	1.000	-	-		X4306
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740