Protein Alignment HDAC11 and hda-11

DIOPT Version :9

• Sequence 1: NP_001247296.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: NP_505699.3
• Gene: hda-11 / 183226
• WormBaseID: WBGene00007953
• Length: 334
• Species: Caenorhabditis elegans
• Alignment Length: 338
• Identity: 138/338 - (40%)
• Similarity: 209/338 - (61%)
• Gaps: 14/338 - (4%)

  Fly    12 EQESEEVVWVKRDDARSAGKLPIVFSRNYAVRFGGLERLHPFDAAKGKHIHKLLCAQLQLDDGSF 76
            |::.:|:..:|      :.:.|||:...|.|...|:|.|||||::|.:.:...|.....:.|.:.
 Worm     3 ERDKDEIFSLK------SYQRPIVYHSEYNVTAFGIEHLHPFDSSKWRRVITHLKEMNLITDETL 61

  Fly    77 YEPTELTKDQLRRIHTREYLKSLRWSMNVACIAEVPLMAFVPNRYIQRSYLRPMRFQAAGSILAG 141
            .||...|.::|.|:|.|:||||:|..:..|.|.|:|.:..:|...|:...|.|:|.||.|::||.
 Worm    62 VEPNLPTFEELTRVHDRKYLKSVRNPIKAAQIVEIPFVGCLPPCIIESKLLHPLRLQAGGTVLAA 126

  Fly   142 KLALDYGWAINLGGGFHHCCSYRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQGNGHE 206
            .|||.:|||||:||||||.....|||||.||||::.|..||:::  .:...::|||||||||||.
 Worm   127 NLALKHGWAINVGGGFHHASHSGGGGFCFYADITMAIFDLFDKK--AIANAIVVDLDAHQGNGHA 189

  Fly   207 RDFNNVAAVYIFDMYNAFVYPRDHVAKESIRCAVELRNYTEDGFYLRQLKRCLMQSLAEFRP--- 268
            |||.:...|::||::|.:|||.|..|::.|..||.:..:|.|..||.:|::.|.|.|.:...
 Worm   190 RDFADNPNVFVFDVFNPYVYPHDREARQFINRAVHVNGHTTDTSYLSELRKQLAQCLIDREKTTP 254

  Fly   269 ---DMVVYNAGTDVLEGDPLGNLAISAEGVIERDRLVFSTFRALGIPVVMLLSGGYLKASAGVIT 330
               |.:::|||||.|.|||||.:.:|.:.:|.||.:||:..::.|||:.|:.||||.|.:|.:|.
 Worm   255 PGFDFIMFNAGTDCLLGDPLGAMKLSPQCIIARDEVVFNLAKSKGIPICMVTSGGYQKDNALLIA 319

  Fly   331 DSIVNLRLQGLLN 343
            .||.||:.:.|::
 Worm   320 KSIENLQSKNLIS 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_001247296.1	HDAC_classIV	51..336	CDD:212519	124/290 (43%)
hda-11	NP_505699.3	HDAC_classIV	36..325	CDD:212519	124/290 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166325
Domainoid	1	1.000	238	1.000	Domainoid score	I1287
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11743
Inparanoid	1	1.050	261	1.000	Inparanoid score	I1910
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57761
OrthoDB	1	1.010	-	-		D1037375at2759
OrthoFinder	1	1.000	-	-		FOG0006007
OrthoInspector	1	1.000	-	-		oto19830
orthoMCL	1	0.900	-	-		OOG6_103672
Panther	1	1.100	-	-	LDO	PTHR48252
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3706
SonicParanoid	1	1.000	-	-		X4306
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.800