Protein Alignment HDAC11 and hda-1

DIOPT Version :10

• Sequence 1: NP_733048.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: NP_506599.1
• Gene: hda-1 / 179959
• WormBaseID: WBGene00001834
• Length: 461
• Species: Caenorhabditis elegans
• Alignment Length: 316
• Identity: 84/316 - (26%)
• Similarity: 117/316 - (37%)
• Gaps: 89/316 - (28%)

  Fly    39 NYAVRFGGLERLHPFDAAKGKHIHKLLCAQLQLDDGSFYEPTELTKDQLRRIHTREY-------- 95
            ||.: :..||...||.|                   ||        :.:.|.|:.||
 Worm    48 NYGL-YRNLEIFRPFPA-------------------SF--------EDMTRFHSDEYMTFLKSAN 84

  Fly    96 ---LKS-----LRWSMNVACIAEVPLMAFVPNRYIQRSYLRPMRFQAAGSILA----GKLALDYG 148
               |||     |::::...|.....|..|             .:..:.||:.|    .|..:|.
 Worm    85 PDNLKSFNKQMLKFNVGEDCPLFDGLYEF-------------CQLSSGGSLAAATKLNKQKVDI- 135

  Fly   149 WAINLGGGFHHCCSYRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQGNGHERDFNNVA 213
             |||..||.||.......|||...||.|.|:.|.:..    :|::.||:|.|.|:|.|..|....
 Worm   136 -AINWMGGLHHAKKSEASGFCYTNDIVLGILELLKYH----KRVLYVDIDVHHGDGVEEAFYTTD 195

  Fly   214 AVYI--FDMYNAFVYPRDHVAKE---------SIRCAVELRNYTEDGFYLRQLKRCLMQSLAEFR 267
            .|..  |..|..| :|.....|:         |:.  |.||:...|..|....|..:.:.:..|.
 Worm   196 RVMTVSFHKYGDF-FPGTGDLKDIGAGKGKLYSVN--VPLRDGITDVSYQSIFKPIMTKVMERFD 257

  Fly   268 PDMVVYNAGTDVLEGDPLG--NLAISAEGVIERDRLVFSTFRALGIPVVMLLSGGY 321
            |..||...|.|.|.||.||  ||.:...|...|      .||:..:|::|:..|||
 Worm   258 PCAVVLQCGADSLNGDRLGPFNLTLKGHGECAR------FFRSYNVPLMMVGGGGY 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_733048.1	HDAC_classIV	51..336	CDD:212519	80/304 (26%)
hda-1	NP_506599.1	HDAC_classI	18..323	CDD:212517	84/316 (27%)