Protein Alignment HDAC11 and hda-10

DIOPT Version :9

• Sequence 1: NP_001247296.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: NP_496910.1
• Gene: hda-10 / 175039
• WormBaseID: WBGene00001838
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 285
• Identity: 64/285 - (22%)
• Similarity: 117/285 - (41%)
• Gaps: 39/285 - (13%)

  Fly    81 ELTKDQLRRIHTREYLKSLRWSMNVACIAEVPLMAFVPNRYIQRSYLRPMRFQAAGSI------L 139
            |..:.::..:||:.|:..::.:..:....:........:.|:..:.....:..|..||      :
 Worm    58 EAEESEILAVHTKRYVDDVKSTETMTVEQQESFCTKYEDIYVNSATWHRAKLAAGASIDLMTSVM 122

  Fly   140 AGKLALDYGWAINLGGGFHHCCSYRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQGNG 204
            |.|..   |.|.....| ||.....|.|||.:.::::......:..    ::::|||.|.|.|||
 Worm   123 AAKRP---GIAFIRPPG-HHAMPDEGCGFCIFNNVAIAAKAAIQNG----QKVLIVDYDVHAGNG 179

  Fly   205 -----HERDFNNVAAVYIFDMYNAFVYPR------DHVAKESIRCAVELRNYTEDGFYLRQLKRC 258
                 .:....||..:.|....|...:|.      .|..|.:|...:.....| |..|.......
 Worm   180 TQECVEQMGEGNVQLISIHRYENGHFWPNMPQTGIYHNYKNTINLPLNTIGLT-DADYHALFTHI 243

  Fly   259 LMQSLAEFRPDMVVYNAGTDVLEGDPLGNLAISAEGVIERDRLVFSTFRALGIPVVMLLSGGY-L 322
            ::.::..|:||:::.::|.|...|||.|::.::..|.....|::..|    ||||..||.||| |
 Worm   244 ILPTIHAFQPDLLLVSSGFDASIGDPEGSMQVTPAGFATMIRMLIDT----GIPVAALLEGGYFL 304

  Fly   323 KASA--------GVITDSIVNLRLQ 339
            .|.|        .::.:.|..:|::
 Worm   305 DALAADSEWVLRALLGEEIPRIRVE 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_001247296.1	HDAC_classIV	51..336	CDD:212519	63/280 (23%)
hda-10	NP_496910.1	HDAC10_HDAC6-dom1	20..346	CDD:212526	64/285 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810