Protein Alignment HDAC11 and Hdac10

DIOPT Version :9

• Sequence 1: NP_001247296.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: XP_006520600.1
• Gene: Hdac10 / 170787
• MGIID: 2158340
• Length: 667
• Species: Mus musculus
• Alignment Length: 342
• Identity: 76/342 - (22%)
• Similarity: 137/342 - (40%)
• Gaps: 64/342 - (18%)

  Fly     5 TERVHHEEQESEEVVWVKRDDARSAGKLPIVFSRNYAVRFGGLERL-HPFDAAKGKHI-HKLLCA 67
            |..|:||:..:..::|   ||.....:.|              ||| ...|..:.:.: .:.||
Mouse     3 TALVYHEDMTATRLLW---DDPECEIECP--------------ERLTAALDGLRQRGLEERCLC- 49

  Fly    68 QLQLDDGSFYEPTELTKDQLRRIHTREYLKSLRWSMNV------ACIAEVPLMAFVPNRYIQRSY 126
                     ....|.::::|..:|:.||:..::.:..:      |...:...:.|.|:.:.....
Mouse    50 ---------LSACEASEEELGLVHSPEYIALVQKTQTLDKEELHALSKQYNAVYFHPDTFHCARL 105

  Fly   127 LRPMRFQAAGSILAGKLALDYGWAINLGGGFHHCCSYRGGGFCPYADISLLIVRLFEQEPFRVRR 191
            ......|...::|.|  |:..|.|:....| ||.......|||.:.:::|  .....::.:.::|
Mouse   106 AAGAALQLVDAVLTG--AVHNGLALVRPPG-HHSQRAAANGFCVFNNVAL--AAKHAKQKYGLQR 165

  Fly   192 IMIVDLDAHQGNGHERDFNNVAAVYIFDMY---NAFVYPRDHVAKESIRCAV---ELRNYT---- 246
            |:|||.|.|.|.|.:..||:..:|..|..:   :...:|   ...||...||   :.:.:|
Mouse   166 ILIVDWDVHHGQGIQYIFNDDPSVLYFSWHRYEHGSFWP---FLPESDADAVGQGQGQGFTVNLP 227

  Fly   247 ------EDGFYLRQLKRCLMQSLAEFRPDMVVYNAGTDVLEGDPLGNLAISAEGVIERDRLVFST 305
                  .:..||......|:....||.|::|:.:||.|...|||.|.:..:.|......:|:
Mouse   228 WNQVGMGNADYLAAFLHVLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLL--- 289

  Fly   306 FRAL-GIPVVMLLSGGY 321
             :.| |..:..:|.|||
Mouse   290 -QVLAGGRICAVLEGGY 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_001247296.1	HDAC_classIV	51..336	CDD:212519	65/295 (22%)
Hdac10	XP_006520600.1	Arginase_HDAC	18..354	CDD:388375	72/327 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810