Protein Alignment HDAC11 and HDAC3

DIOPT Version :10

• Sequence 1: NP_733048.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: XP_322018.5
• Gene: HDAC3 / 1282023
• VectorBaseID: AGAMI1_000192
• Length: 433
• Species: Anopheles gambiae
• Alignment Length: 316
• Identity: 73/316 - (23%)
• Similarity: 122/316 - (38%)
• Gaps: 84/316 - (26%)

  Fly    51 HPFDAAKGKHIHKL-----LCAQLQLDDGSFYEPTELTKDQLRRIHTREYLKSLRWSMNVACIAE 110
            ||....:...||.|     |..::|:     |.|.:.:...:.|.|:.||::
Mosquito    23 HPMKPHRLSVIHHLVMNYGLHKKMQI-----YRPYKASAHDMCRFHSDEYIE------------- 69

  Fly   111 VPLMAFVPNRYIQRSYLRPMRFQA---------------------------AGSILAGKLALDYG 148
                      ::||  :.|...|.                           .|:.|.|...|::.
Mosquito    70 ----------FLQR--VTPQNIQGYTKCLSVFNVGDDCPVFDGLFEFCAMYTGASLEGAQKLNHN 122

  Fly   149 WA---INLGGGFHHCCSYRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQGNGHERDF- 209
            .:   ||..||.||...:...|||...||.:.|:.|.:..|    |::.:|:|.|.|:|.:..|
Mosquito   123 HSDICINWSGGLHHAKKFEASGFCYVNDIVIGILELLKYHP----RVLYIDIDVHHGDGVQEAFY 183

  Fly   210 --NNVAAVYIFDMYNAFVYPRD----HVAKESIR---CAVELRNYTEDGFYLRQLKRCLMQSLAE 265
              :.|..| .|..|..:.:|..    .:..||.|   ..|.|:...:|..|::..|..:...:..
Mosquito   184 LTDRVMTV-SFHKYGNYFFPGTGDMYEIGAESGRYYSVNVPLKEGIDDQSYVQVFKPVISAVMEF 247

  Fly   266 FRPDMVVYNAGTDVLEGDPLGNLAISAEGVIERDRLVFSTFRALGIPVVMLLSGGY 321
            ::|..:|...|.|.|.||.||..::|.:|..|..:.|    :.|.:|.:::..|||
Mosquito   248 YQPTAIVLQCGADSLAGDRLGCFSLSTKGHGECVKFV----KDLNVPTLVVGGGGY 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_733048.1	HDAC_classIV	51..336	CDD:212519	73/316 (23%)
HDAC3	XP_322018.5	HDAC3	4..384	CDD:212529	73/316 (23%)