Protein Alignment HDAC11 and HDAC4

DIOPT Version :10

• Sequence 1: NP_733048.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: XP_061497881.1
• Gene: HDAC4 / 1271834
• VectorBaseID: AGAMI1_002562
• Length: 1199
• Species: Anopheles gambiae
• Alignment Length: 368
• Identity: 84/368 - (22%)
• Similarity: 138/368 - (37%)
• Gaps: 100/368 - (27%)

  Fly    48 ERLHP------FDAAKGKHI--------HKLLCAQLQ------LDDGSFYEPTEL-----TKDQL 87
            ::|.|      ||:...||:        |.....:||      |..|......:|     |:::|
Mosquito   762 QKLRPATTGLAFDSLMLKHVCACGDNANHPEHSGRLQSIWARLLGTGLAIRCDKLRSRKATQEEL 826

  Fly    88 RRIHT-------------REYLKSLRWS-MNVACIAEVPLMAFVPNRYIQRSYLRPMRFQAAGSI 138
            :.:||             |:.:.:.|.| :.:||......:....|.:          ..||.:.
Mosquito   827 QTVHTEGHALLFGTSQLNRQKVDTSRVSFVRLACGGVGVDLDTTWNEH----------HTAAAAR 881

  Fly   139 LAGKLALDYGWAINLG---GGF-------HHCCSYRGGGFCPYADISLLIVRLFEQEPFRVRRIM 193
            :|....:|..:.:..|   .||       ||..:....|||.:..|:|....|..:.|..:|||:
Mosquito   882 MAAGCVIDLSYKVARGENRNGFAVVRPPGHHAEADAAMGFCFFNSIALAARLLRHRMPHEMRRIL 946

  Fly   194 IVDLDAHQGNGHERDFNNVAAVYIFDMY---NAFVYPRDHVAKESIRCAV--------------E 241
            |||.|.|.|||.::.|.:.|:|....::   :...:|......|   |.|              .
Mosquito   947 IVDWDVHHGNGTQQAFYDDASVLYLSVHRHDDGNFFPGTGGPAE---CGVGTGLGYNVNVAWSGG 1008

  Fly   242 LRNYTEDGFYLRQLKRCLMQSLAEFRPDMVVYNAGTDVLEGD--PLGNLAISAE--GVIERDRLV 302
            :.....|..||...:..:|....:|.||:|:.:||.|...|.  |||...:|..  |.:.|:.:.
Mosquito  1009 VNPPLGDAEYLAAFRTVVMPIARDFAPDIVLVSAGFDAAVGHPAPLGGYVVSPACFGHLTRELMQ 1073

  Fly   303 FSTFRALGIPVVMLLSGGY------------LKASAGVITDSI 333
            .:..:     :|:.|.|||            ::|..|..|.||
Mosquito  1074 LANGK-----IVLALEGGYDLPAICDSAEECVRALLGESTSSI 1111

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_733048.1	HDAC_classIV	51..336	CDD:212519	83/365 (23%)
HDAC4	XP_061497881.1	None