Protein Alignment HDAC11 and HDAC6

DIOPT Version :10

• Sequence 1: NP_733048.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: XP_061502723.1
• Gene: HDAC6 / 1271709
• VectorBaseID: AGAMI1_007942
• Length: 1114
• Species: Anopheles gambiae
• Alignment Length: 320
• Identity: 74/320 - (23%)
• Similarity: 121/320 - (37%)
• Gaps: 68/320 - (21%)

  Fly    38 RNYAVRFGGLERLHPFDAAKGKHIHKLLCAQLQLDDGSFYEPTEL-TKDQLRRIHTREYLKSLRW 101
            ||.|      |:.||....:...|.:.|....||.......|..| |.::|..:|..|:::.
Mosquito   544 RNSA------EKWHPEQPERIAKIMQRLTGDYQLAQRMKRLPGRLATTEELCLVHGPEHVRL--- 599

  Fly   102 SMNVACIAEVPLMAFVPNRYIQRSYLRP----MRFQAAGSILA-------GKLALDYGWAINLGG 155
               :..:.:...|....::| ...|..|    ....|.||:|.       |:..  .|..:....
Mosquito   600 ---IGEVCQSSTMKQTADQY-NSIYFHPSTDASARMATGSVLTVVEDVLEGRTR--SGVCVVRPP 658

  Fly   156 GFHHCCSYRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQGNGHERDFNN-----VAAV 215
            | ||..:....|||.|..|::......::  :.:||::|||.|.|.|||.:..|..     ..:|
Mosquito   659 G-HHAEADTPHGFCIYNSIAVAARHAVKR--YGLRRVLIVDWDVHHGNGTQHIFEQDPHVLYVSV 720

  Fly   216 YIFDMYNAFVYPRDHVAKESIRCAVELRNYT----------EDGFYLRQLKRCLMQSLAEFRPDM 270
            :.:|  |...:||...|..::..:...|.:.          .|..|:......::....|:.|::
Mosquito   721 HRYD--NGAFFPRSTDADYTVVGSGPGRGFNVNIPWNRKGMGDPEYVAAFHSVILPIAYEYEPEL 783

  Fly   271 VVYNAGTDVLEGDPLGNLAISAE---------GVIERDRLVFSTFRALGIPVVMLLSGGY 321
            |:.:||.|...|||||...::.|         .|:...||            |:.|.|||
Mosquito   784 VLVSAGFDAAIGDPLGGCRVTPEAYGHFTQWLSVLAGGRL------------VLCLEGGY 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_733048.1	HDAC_classIV	51..336	CDD:212519	70/307 (23%)
HDAC6	XP_061502723.1	None