Protein Alignment HDAC11 and hdac12

DIOPT Version :10

• Sequence 1: NP_733048.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: XP_001920667.4
• Gene: hdac12 / 100148903
• ZFINID: ZDB-GENE-131121-613
• Length: 354
• Species: Danio rerio
• Alignment Length: 306
• Identity: 96/306 - (31%)
• Similarity: 142/306 - (46%)
• Gaps: 45/306 - (14%)

  Fly    32 LPIVFSRNYAVRF-GGLERLHPFDAAKGKHIHKLLCAQLQLDDGSFYEPTELTKDQLRRIHTREY 95
            ||||    :.|:| ..|...|.|...|...|.:.|.....:.|...:.|...:::.||.:||.||
Zfish    51 LPIV----HHVKFICELPENHRFPMLKFPKILESLLRDQAITDKQVWAPKIASEELLRCVHTEEY 111

  Fly    96 LKS---------------LRWSMNVACIAEVPLMAFVPNRYIQRSYLRPMRFQAAGSILAGKLAL 145
            |.:               ..||..:                :||     .|::..|::|||::||
Zfish   112 LSNFISGKISEKDQKRSGFPWSSGL----------------VQR-----CRYETGGTLLAGQIAL 155

  Fly   146 DYGWAINLGGGFHHCCSYRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQGNGHERDFN 210
            ..|.|.:..||.||.....|.|||...|:::....|. .||...|:|:|||||.|||:|....|.
Zfish   156 QRGLACSTAGGTHHAFPSHGSGFCLLNDLAVTAKHLI-SEPTPKRKILIVDLDVHQGDGTAFIFK 219

  Fly   211 NVAAVYIFDMYNAFVYPRDHVAKESIRCAVELRNYTEDGFYLRQLKRCLMQSLAEFRPDMVVYNA 275
            :..:|:.|.::....:|   :.|:.....|.|.:.|||..||.:::..|...|..||||:|:|::
Zfish   220 DEPSVFTFSVHCQRNFP---LRKQQSDLDVSLEDGTEDREYLSRVQEHLPWLLESFRPDLVLYDS 281

  Fly   276 GTDVLEGDPLGNLAISAEGVIERDRLVFSTFRALGIPVVMLLSGGY 321
            |.|....|.||.|.::.||:..||..|..|....||||..::.|||
Zfish   282 GVDPHWDDELGKLRLTDEGLYRRDLYVLHTVVKSGIPVATVIGGGY 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC11	NP_733048.1	HDAC_classIV	51..336	CDD:212519	89/286 (31%)
hdac12	XP_001920667.4	HDAC_classIV	67..342	CDD:212519	89/286 (31%)