DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB11 and Anxa9

DIOPT Version :9

Sequence 1:	NP_001259616.1	Gene:	AnxB11 / 32612	FlyBaseID:	FBgn0030749	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001078852.1	Gene:	Anxa9 / 71790	MGIID:	1923711	Length:	345	Species:	Mus musculus

Alignment Length:	303	Identity:	104/303 - (34%)
Similarity:	166/303 - (54%)	Gaps:	4/303 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 NFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTHFGKDLIEDIKSETSGNFE 267
            :|...||...|.||:.|.|.|.|.:::::..||.||||.|.|.|:....:||::.:::..|||.|
Mouse    40 SFSVDKDVQRLLKAIAGQGVDYDTIVDVLTNRSREQRQLISRAFQERTKQDLLKSLQAALSGNLE 104

  Fly   268 KLLVGLLRPIVDYYCAELNDAMAGLGTDEEVLIEILCTLSNMEINTIKNQYLRLYGAHLESELKS 332
            |::|.||:|...:...||..|:...|:.|:|.:|||.|.:...:......|...:....|.::::
Mouse   105 KIVVALLQPAAQFDAQELRTALKTSGSAEDVALEILATRAAPGLQACLAVYKHDFQVEAEEDIRT 169

  Fly   333 ETSGNFKRLLTSLCTAARDE-SGRVDPVAAKNDARELLKAGELRVGTDESMFNMILCQRNYQQLK 396
            ||:|..:.||.:|....|:. ||.:|....:.|.|.|.:|||   .:....:.::|.||:.:.|.
Mouse   170 ETNGILQDLLLALSKGDRESYSGIIDYNLEEQDVRALQQAGE---SSTAGQWVLLLTQRSPEHLI 231

  Fly   397 LIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRLHKAMAGIGTNDTQLIRV 461
            .:|.:|...||..||.||:..|.||....||::...:.|.|.|||::||:|:.....|...|.||
Mouse   232 RVFDQYRRCTGQELEDAIRNCFHGDAQLALISLASMLRNTALYFANKLHQALQETEPNFQVLTRV 296

  Fly   462 IITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYAL 504
            :|:|||.|:..|:..|::.:||||.|.::....|..:.||.||
Mouse   297 LISRSESDLLSIRAEFKKKFGKSLYSSLQDVVRGDCRSALLAL 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB11	NP_001259616.1	Annexin	209..273	CDD:278615	25/63 (40%)
		Annexin	280..345	CDD:278615	17/64 (27%)
		Annexin	364..429	CDD:278615	23/64 (36%)
		Annexin	439..504	CDD:278615	25/64 (39%)
Anxa9	NP_001078852.1	Annexin 1. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	41..112		28/70 (40%)
		Annexin	46..110	CDD:395139	25/63 (40%)
		Annexin 2. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	113..184		19/70 (27%)
		Annexin	117..182	CDD:395139	17/64 (27%)
		Annexin 3. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	197..266		23/71 (32%)
		Annexin	<222..264	CDD:413385	17/41 (41%)
		Annexin 4. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	270..341		29/70 (41%)
		Annexin	274..339	CDD:395139	25/64 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831981
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D856254at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.760