DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB11 and Anxa13

DIOPT Version :9

Sequence 1:	NP_001259616.1	Gene:	AnxB11 / 32612	FlyBaseID:	FBgn0030749	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_081487.1	Gene:	Anxa13 / 69787	MGIID:	1917037	Length:	317	Species:	Mus musculus

Alignment Length:	324	Identity:	147/324 - (45%)
Similarity:	208/324 - (64%)	Gaps:	9/324 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 GHAHRSLPAHREGTPTVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQF 246
            |:.|....:|..|         |||.:||..|.||.||.||||.|:|.::..|::|:||:|::::
Mouse     2 GNRHAKERSHHHG---------FDADRDAKKLYKACKGMGTDEAAIIEVLSSRTSEERQQIKQKY 57

  Fly   247 KTHFGKDLIEDIKSETSGNFEKLLVGLLRPIVDYYCAELNDAMAGLGTDEEVLIEILCTLSNMEI 311
            |..:||||.|.:.||.||||:|..:.||....:|...:|..||.|:||||.:|||||||.||.||
Mouse    58 KEKYGKDLEEVLNSELSGNFKKTALALLDRPNEYAARQLQKAMKGVGTDEAMLIEILCTRSNKEI 122

  Fly   312 NTIKNQYLRLYGAHLESELKSETSGNFKRLLTSLCTAARDESGRVDPVAAKNDARELLKAGELRV 376
            ..||..|.||:|..|||::|.:||||.:::|.||..|:|||...||...|..||::|..|||.|.
Mouse   123 VAIKEAYQRLFGRSLESDVKEDTSGNLRKILVSLLQASRDEEDTVDKELAGQDAKDLYDAGEGRW 187

  Fly   377 GTDESMFNMILCQRNYQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFA 441
            ||||..||.:|.:|:|:||:..||.|:.:.|..:|:.|::|.|||:.:..:.|.||..:...|||
Mouse   188 GTDELAFNEVLAKRSYKQLRATFQAYQILIGKDMEETIEEETSGDLKKAYLTIVRCAQDLEGYFA 252

  Fly   442 SRLHKAMAGIGTNDTQLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALV 505
            ..|:|||.|:||::..|||:|:||:|:|:..||..|:..|.|||...:..||||.::..|.||:
Mouse   253 DLLYKAMKGMGTDEETLIRIIVTRAEVDLQGIKAKFQEKYQKSLSDMVHSDTSGDFRKLLVALL 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB11	NP_001259616.1	Annexin	209..273	CDD:278615	31/63 (49%)
		Annexin	280..345	CDD:278615	35/64 (55%)
		Annexin	364..429	CDD:278615	28/64 (44%)
		Annexin	439..504	CDD:278615	30/64 (47%)
Anxa13	NP_081487.1	Annexin 1. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	15..86		35/70 (50%)
		Annexin	19..84	CDD:278615	31/64 (48%)
		Annexin 2. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	87..158		37/70 (53%)
		Annexin	91..156	CDD:278615	35/64 (55%)
		Annexin 3. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	170..242		30/71 (42%)
		Annexin	174..240	CDD:278615	28/65 (43%)
		Annexin 4. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	246..317		32/71 (45%)
		Annexin	250..315	CDD:278615	30/64 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831961
Domainoid	1	1.000	74	1.000	Domainoid score	I9101
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.860