DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB11 and anxa5a

DIOPT Version :9

Sequence 1:	NP_001259616.1	Gene:	AnxB11 / 32612	FlyBaseID:	FBgn0030749	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001107054.1	Gene:	anxa5a / 557578	ZFINID:	ZDB-GENE-080220-29	Length:	316	Species:	Danio rerio

Alignment Length:	310	Identity:	130/310 - (41%)
Similarity:	200/310 - (64%)	Gaps:	2/310 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 TVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTHFGKDLIEDIKSE 261
            :|.|..:|:|..||..|||||||.|||||.::.::..|||:|||||:..:|..|||||::|::||
Zfish     6 SVKPFVHFNAKHDAEVLRKAMKGIGTDEDTILMLLAARSNDQRQEIKAAYKKAFGKDLVKDLRSE 70

  Fly   262 TSGNFEKLLVGLLRPIVDYYCAELNDAMAGLGTDEEVLIEILCTLSNMEINTIKNQYLRLYGAHL 326
            ..|..|.|:|.|:.|...|...||:.|:.|:||:::||||||.:.:..||..|...|.:.:|..|
Zfish    71 LGGKLEDLIVALMAPPTIYDANELHKAIKGVGTEDQVLIEILASRTCEEIKEIVKAYKKEHGGKL 135

  Fly   327 ESELKSETSGNFKRLLTSLCTAARDESGRVDPVAAKNDARELLKAGELRVGTDESMFNMILCQRN 391
            |.::..:|||:::::|..|..|.|:|.  ||....:.||:||..|||.:.||||..|..||..|:
Zfish   136 EKDIMGDTSGHYQKMLVILVQAGREEG--VDESRVEKDAKELFAAGEEKFGTDEDKFINILGNRS 198

  Fly   392 YQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRLHKAMAGIGTNDT 456
            .:.|:.:|:.|:.:.|..:|:::|:|.:|::...|:|:.:|..:...|||..|.::|...||:|.
Zfish   199 AEHLRKVFEAYKKIAGCDIEESLKEECTGNLEALLLAVVKCAKSVPAYFAECLRESMRRAGTDDE 263

  Fly   457 QLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALVG 506
            .|||::::|||.||.||:.|:::.||.||.|.|:.||.|.|:.||..|.|
Zfish   264 TLIRIMVSRSERDMLDIRAAYKKKYGDSLYSTIQEDTDGDYQKALLYLCG 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB11	NP_001259616.1	Annexin	209..273	CDD:278615	35/63 (56%)
		Annexin	280..345	CDD:278615	24/64 (38%)
		Annexin	364..429	CDD:278615	24/64 (38%)
		Annexin	439..504	CDD:278615	31/64 (48%)
anxa5a	NP_001107054.1	Annexin	17..82	CDD:278615	35/64 (55%)
		Annexin	89..154	CDD:278615	24/64 (38%)
		Annexin	171..236	CDD:278615	24/64 (38%)
		Annexin	246..311	CDD:278615	31/64 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574818
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	1	1.000	-	-		mtm6419
orthoMCL	1	0.900	-	-		OOG6_100522
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.660