DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB11 and anxa4

DIOPT Version :9

Sequence 1:	NP_001259616.1	Gene:	AnxB11 / 32612	FlyBaseID:	FBgn0030749	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001016047.1	Gene:	anxa4 / 548801	XenbaseID:	XB-GENE-854498	Length:	321	Species:	Xenopus tropicalis

Alignment Length:	310	Identity:	154/310 - (49%)
Similarity:	203/310 - (65%)	Gaps:	0/310 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 TVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTHFGKDLIEDIKSE 261
            |:.|.|||:|..|...|||||||.||||||:|::|..|:..|||||:..:||..||||.:|:|||
Frog     9 TIKPYANFNAADDVQKLRKAMKGAGTDEDAIIDVIANRTLSQRQEIKTAYKTTIGKDLEDDLKSE 73

  Fly   262 TSGNFEKLLVGLLRPIVDYYCAELNDAMAGLGTDEEVLIEILCTLSNMEINTIKNQYLRLYGAHL 326
            .:|||||::|||:.|...|...||..||.|.||||..|||||.:.|..||..|...|...||..|
Frog    74 LTGNFEKVIVGLITPSTLYDVEELKKAMKGAGTDEGCLIEILASRSAEEIKNINITYRIKYGKSL 138

  Fly   327 ESELKSETSGNFKRLLTSLCTAARDESGRVDPVAAKNDARELLKAGELRVGTDESMFNMILCQRN 391
            |.::.|:||..|:|:|.||....||:|..|:...||.||.||.:|||.:.||||..|..|||.||
Frog   139 EDDICSDTSFMFQRVLVSLAAGGRDQSTNVNEALAKQDANELYEAGEKKWGTDEVKFLTILCSRN 203

  Fly   392 YQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRLHKAMAGIGTNDT 456
            ...|..:|.||:.:....||.:||.|.||...:.|:|:.:|:.::..|||.||:|:|.|:||:|.
Frog   204 RNHLLKVFDEYKKIAKKDLEASIKSEMSGHFEDALLAVVKCLRSRPGYFAERLYKSMKGLGTDDK 268

  Fly   457 QLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALVG 506
            .||||:::|.||||.:|:..|:::|||||.|:||||.||.|:..|..|.|
Frog   269 TLIRVMVSRCEIDMLEIRSEFKKMYGKSLHSFIKGDCSGDYRKVLLKLCG 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB11	NP_001259616.1	Annexin	209..273	CDD:278615	38/63 (60%)
		Annexin	280..345	CDD:278615	30/64 (47%)
		Annexin	364..429	CDD:278615	29/64 (45%)
		Annexin	439..504	CDD:278615	36/64 (56%)
anxa4	NP_001016047.1	Annexin	21..85	CDD:365936	38/63 (60%)
		Annexin	92..157	CDD:365936	30/64 (47%)
		Annexin	175..241	CDD:365936	29/65 (45%)
		Annexin	251..316	CDD:365936	36/64 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	80	1.000	Domainoid score	I8469
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	1	1.000	-	-		mtm14095
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4028
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.040