DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AnxB11 and anxa1c

DIOPT Version :9

Sequence 1:	NP_001259616.1	Gene:	AnxB11 / 32612	FlyBaseID:	FBgn0030749	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_861425.1	Gene:	anxa1c / 494158	ZFINID:	ZDB-GENE-030131-5274	Length:	341	Species:	Danio rerio

Alignment Length:	324	Identity:	127/324 - (39%)
Similarity:	191/324 - (58%)	Gaps:	1/324 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 RSLPAHREG-TPTVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTH 249
            ::.||...| ..||....||:|..||..|:||::..|.||..:|.::.::||.|||:|:..::..
Zfish    18 KAAPAFETGYFGTVKADTNFNAQNDAAKLKKAIETKGVDEATIIEVLAKKSNAQRQQIKAAYQQS 82

  Fly   250 FGKDLIEDIKSETSGNFEKLLVGLLRPIVDYYCAELNDAMAGLGTDEEVLIEILCTLSNMEINTI 314
            .||.|.:.:|...|.:.|.:::.||....:|...|:.:|:.||||.|.||.|||.|.||.||..:
Zfish    83 AGKPLADALKKALSSHLEDVVLALLMTPSEYDAFEMKNALKGLGTSENVLSEILGTRSNKEITAL 147

  Fly   315 KNQYLRLYGAHLESELKSETSGNFKRLLTSLCTAARDESGRVDPVAAKNDARELLKAGELRVGTD 379
            ||.:..:||..||.::.|:..||.:..|.:||.|.|.|...:|...||:||:.|.:|||.|:||.
Zfish   148 KNSFKEVYGEMLEEDINSDVKGNLETALLALCKATRSEDRNIDDAQAKSDAKALFEAGENRIGTV 212

  Fly   380 ESMFNMILCQRNYQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRL 444
            .|:...||..|:..||..|||.|..::...|.|.::.|.||.:.:.|:.:.:...||..|||.:|
Zfish   213 CSVLIDILTNRSEAQLCKIFQYYSQLSKDGLAKDLEGELSGHLEDCLMTLVKAAWNKPAYFAEKL 277

  Fly   445 HKAMAGIGTNDTQLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALVGEQ 508
            ..||.|:||:|..|||:|::|||||:..|...::|:|||:|:..|:.:|.|.|:..|..|.|.|
Zfish   278 QHAMKGLGTDDNTLIRIIVSRSEIDLLKIMQEYKRMYGKTLQEAIQSETKGDYEKILLVLCGSQ 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB11	NP_001259616.1	Annexin	209..273	CDD:278615	21/63 (33%)
		Annexin	280..345	CDD:278615	28/64 (44%)
		Annexin	364..429	CDD:278615	25/64 (39%)
		Annexin	439..504	CDD:278615	30/64 (47%)
anxa1c	NP_861425.1	Annexin	42..106	CDD:278615	21/63 (33%)
		Annexin	113..178	CDD:278615	28/64 (44%)
		Annexin	197..262	CDD:278615	25/64 (39%)
		Annexin	272..337	CDD:278615	30/64 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574837
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.860