DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB11 and anxa3a

DIOPT Version :9

Sequence 1:	NP_001259616.1	Gene:	AnxB11 / 32612	FlyBaseID:	FBgn0030749	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001004632.2	Gene:	anxa3a / 447893	ZFINID:	ZDB-GENE-040912-58	Length:	340	Species:	Danio rerio

Alignment Length:	322	Identity:	129/322 - (40%)
Similarity:	195/322 - (60%)	Gaps:	4/322 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 PAHREGTP----TVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTH 249
            ||.....|    |:...|||:..:|...||||::|.||:|..||.|:..||:.|:|||.:.::..
Zfish    16 PASFAAAPGERGTIKAKANFNVSEDVAALRKAIEGVGTNEKTLIEILTHRSSSQKQEIAKAYRET 80

  Fly   250 FGKDLIEDIKSETSGNFEKLLVGLLRPIVDYYCAELNDAMAGLGTDEEVLIEILCTLSNMEINTI 314
            ..:.|..|:|.||.|||||:||||.||:.......|::|:.|.|||..:|||||.:.:|.:|..:
Zfish    81 TKRILANDLKGETHGNFEKVLVGLARPLAVNDAEWLHEALKGAGTDNNILIEILSSRTNKQIKEL 145

  Fly   315 KNQYLRLYGAHLESELKSETSGNFKRLLTSLCTAARDESGRVDPVAAKNDARELLKAGELRVGTD 379
            ...|.......|...||:|.||::.:.:..|...||||:..|:...|:.||:.|.:|||.::|||
Zfish   146 SAAYAEETKKTLTQALKTEVSGHYGKAIILLAEGARDENPSVNVDKAREDAQALYQAGEKKLGTD 210

  Fly   380 ESMFNMILCQRNYQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRL 444
            ||.|..|||:|::.||:....||:..:.::|:|:|:||.||::.|.|::|.:|..:...|||.:|
Zfish   211 ESKFIEILCKRSFPQLRQTILEYKNFSKNTLQKSIEKEMSGNLEELLVSIVKCAISTPAYFAEKL 275

  Fly   445 HKAMAGIGTNDTQLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALVG 506
            :|:|.|.||::|.|.||:::|.|:||.||:..::.||..||...|..|.||.|...|..:.|
Zfish   276 NKSMKGAGTDETTLTRVMVSRGEVDMLDIRAEYKTLYKSSLYKAISSDVSGDYADCLKMICG 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB11	NP_001259616.1	Annexin	209..273	CDD:278615	30/63 (48%)
		Annexin	280..345	CDD:278615	20/64 (31%)
		Annexin	364..429	CDD:278615	29/64 (45%)
		Annexin	439..504	CDD:278615	29/64 (45%)
anxa3a	NP_001004632.2	Annexin	40..104	CDD:306660	30/63 (48%)
		Annexin	112..176	CDD:306660	20/63 (32%)
		Annexin	195..260	CDD:306660	29/64 (45%)
		Annexin	270..335	CDD:306660	29/64 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574842
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100522
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.660