DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB11 and anxa6

DIOPT Version :9

Sequence 1:	NP_001259616.1	Gene:	AnxB11 / 32612	FlyBaseID:	FBgn0030749	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001002038.2	Gene:	anxa6 / 353363	ZFINID:	ZDB-GENE-030707-3	Length:	667	Species:	Danio rerio

Alignment Length:	315	Identity:	140/315 - (44%)
Similarity:	209/315 - (66%)	Gaps:	0/315 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 REGTPTVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTHFGKDLIE 256
            :|...|||...:|||..||..|..||||||:|::|::::|..||:.|||||:..:|:.:|||||:
Zfish     3 KEFRGTVVDHPDFDAGSDAEALYNAMKGFGSDKEAILDLITSRSSAQRQEIRTAYKSQYGKDLID 67

  Fly   257 DIKSETSGNFEKLLVGLLRPIVDYYCAELNDAMAGLGTDEEVLIEILCTLSNMEINTIKNQYLRL 321
            |:|.|.:|.||:|:|||:||...:...|:.||:.|:||||:.|||||.:.:|.:|:.:...|...
Zfish    68 DLKYELTGKFERLIVGLMRPPAYHDAKEIKDAIKGVGTDEKCLIEILASRTNEQIHALVAAYSDA 132

  Fly   322 YGAHLESELKSETSGNFKRLLTSLCTAARDESGRVDPVAAKNDARELLKAGELRVGTDESMFNMI 386
            ||..||:::..:|||:||::|..|....|:|...|.....:.||:||.:|||.:.||||:.|.|:
Zfish   133 YGRDLEADVIGDTSGHFKKMLVVLLQGTREEDDVVSEDLVEEDAQELYEAGEAQWGTDEAKFIML 197

  Fly   387 LCQRNYQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRLHKAMAGI 451
            |..|:...|:|:|.||:.:...|:|.:||.|.|||....::|:.:|:.::..:||.||:|:|.|:
Zfish   198 LGNRSVTHLQLVFDEYQKIAEKSIEDSIKSELSGDFERLMLAVVQCIRSRPMFFAKRLYKSMKGL 262

  Fly   452 GTNDTQLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALVG 506
            ||.|..|||::::||||||.||:..|...|.|||.:.|:.||||.||..|..|.|
Zfish   263 GTADNTLIRIMVSRSEIDMLDIRECFRLRYEKSLYNMIQDDTSGDYKRTLLKLCG 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB11	NP_001259616.1	Annexin	209..273	CDD:278615	33/63 (52%)
		Annexin	280..345	CDD:278615	26/64 (41%)
		Annexin	364..429	CDD:278615	28/64 (44%)
		Annexin	439..504	CDD:278615	34/64 (53%)
anxa6	NP_001002038.2	Annexin	20..84	CDD:278615	33/63 (52%)
		Annexin	91..156	CDD:278615	26/64 (41%)
		Annexin	175..240	CDD:278615	28/64 (44%)
		Annexin	250..315	CDD:278615	34/64 (53%)
		Annexin	363..427	CDD:278615
		Annexin	434..499	CDD:278615
		Annexin	517..582	CDD:278615
		Annexin	592..662	CDD:278615
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574839
Domainoid	1	1.000	88	1.000	Domainoid score	I7934
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850