Protein Alignment AnxB11 and ANXA4

DIOPT Version :10

• Sequence 1: NP_727978.1
• Gene: AnxB11 / 32612
• FlyBaseID: FBgn0030749
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001144.1
• Gene: ANXA4 / 307
• HGNCID: 542
• Length: 321
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 152/310 - (49%)
• Similarity: 213/310 - (68%)
• Gaps: 0/310 - (0%)

  Fly   197 TVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTHFGKDLIEDIKSE 261
            ||..|:.|:|::||..|||||||.||||||:|:::..|:..|||||:..:|:..|:|||:|:|||
Human     9 TVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLIDDLKSE 73

  Fly   262 TSGNFEKLLVGLLRPIVDYYCAELNDAMAGLGTDEEVLIEILCTLSNMEINTIKNQYLRLYGAHL 326
            .|||||:::||::.|.|.|...||..||.|.||||..|||||.:.:..||..|...|.:.||..|
Human    74 LSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRISQTYQQQYGRSL 138

  Fly   327 ESELKSETSGNFKRLLTSLCTAARDESGRVDPVAAKNDARELLKAGELRVGTDESMFNMILCQRN 391
            |.:::|:||..|:|:|.||....|||...:|....:.||::|.:|||.:.||||..|..:||.||
Human   139 EDDIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDLYEAGEKKWGTDEVKFLTVLCSRN 203

  Fly   392 YQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRLHKAMAGIGTNDT 456
            ...|..:|.||:.::...:|::||.|.||...:.|:||.:|:.||:.|||.:|:|:|.|:||:|.
Human   204 RNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRNKSAYFAEKLYKSMKGLGTDDN 268

  Fly   457 QLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALVG 506
            .||||:::|:||||.||:..|:|||||||.|:|||||||.|:..|..|.|
Human   269 TLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSFIKGDTSGDYRKVLLVLCG 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AnxB11	NP_727978.1	DUF3432	<79..>119	CDD:403204
		Annexin	209..273	CDD:395139	37/63 (59%)
		Annexin	280..345	CDD:395139	29/64 (45%)
		Annexin	364..429	CDD:395139	26/64 (41%)
		Annexin	439..504	CDD:395139	39/64 (61%)
ANXA4	NP_001144.1	Annexin	21..85	CDD:395139	37/63 (59%)
		Annexin	92..157	CDD:395139	29/64 (45%)
		Annexin	175..241	CDD:395139	26/65 (40%)
		Annexin	251..316	CDD:395139	39/64 (61%)