DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AnxB11 and Anxa1

DIOPT Version :9

Sequence 1:	NP_001259616.1	Gene:	AnxB11 / 32612	FlyBaseID:	FBgn0030749	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_037036.1	Gene:	Anxa1 / 25380	RGDID:	2118	Length:	346	Species:	Rattus norvegicus

Alignment Length:	316	Identity:	123/316 - (38%)
Similarity:	181/316 - (57%)	Gaps:	2/316 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   193 EGTP--TVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTHFGKDLI 255
            :|.|  .|.|..:|:...|...|.||:...|.||..:|:|:.:|:|.|||:|:..:....||.|.
  Rat    29 KGGPGSAVSPYPSFNPSSDVAALHKAIMVKGVDEATIIDILTKRTNAQRQQIKAAYLQETGKPLD 93

  Fly   256 EDIKSETSGNFEKLLVGLLRPIVDYYCAELNDAMAGLGTDEEVLIEILCTLSNMEINTIKNQYLR 320
            |.:|...:|:.|::::.:|:....:...||..||.||||||:.|||||.|.||.:|..|...|..
  Rat    94 ETLKKALTGHLEEVVLAMLKTPAQFDADELRAAMKGLGTDEDTLIEILTTRSNQQIREITRVYRE 158

  Fly   321 LYGAHLESELKSETSGNFKRLLTSLCTAARDESGRVDPVAAKNDARELLKAGELRVGTDESMFNM 385
            .....|..::.|:|||:|:..|.:|....|.|...|:...|..|||.|.:|||.|.|||.::||.
  Rat   159 ELKRDLAKDITSDTSGDFRNALLALAKGDRCEDMSVNQDLADTDARALYEAGERRKGTDVNVFNT 223

  Fly   386 ILCQRNYQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRLHKAMAG 450
            ||..|:|..|:.:||.|...:.|.:.||:..|..||:.:.|..|.:|.|:...:||.:|::||.|
  Rat   224 ILTTRSYPHLRKVFQNYRKYSQHDMNKALDLELKGDIEKCLTTIVKCATSTPAFFAEKLYEAMKG 288

  Fly   451 IGTNDTQLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALVG 506
            .||....|||::::||||||.:|||.:::.||..|...|..:|.|.|:..|.||.|
  Rat   289 AGTRHKTLIRIMVSRSEIDMNEIKVFYQKKYGIPLCQAILDETKGDYEKILVALCG 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB11	NP_001259616.1	Annexin	209..273	CDD:278615	22/63 (35%)
		Annexin	280..345	CDD:278615	28/64 (44%)
		Annexin	364..429	CDD:278615	28/64 (44%)
		Annexin	439..504	CDD:278615	28/64 (44%)
Anxa1	NP_037036.1	Annexin 1. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	42..113		23/70 (33%)
		Annexin	47..111	CDD:395139	22/63 (35%)
		Annexin 2. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	114..185		29/70 (41%)
		Annexin	118..183	CDD:395139	28/64 (44%)
		Annexin 3. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	197..269		30/71 (42%)
		Annexin	202..267	CDD:395139	28/64 (44%)
		Annexin 4. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	273..344		30/70 (43%)
		Annexin	277..342	CDD:395139	28/64 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335643
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.760