Protein Alignment AnxB11 and nex-2

DIOPT Version :9

• Sequence 1: NP_001259616.1
• Gene: AnxB11 / 32612
• FlyBaseID: FBgn0030749
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001022755.1
• Gene: nex-2 / 176446
• WormBaseID: WBGene00003589
• Length: 497
• Species: Caenorhabditis elegans
• Alignment Length: 514
• Identity: 209/514 - (40%)
• Similarity: 276/514 - (53%)
• Gaps: 72/514 - (14%)

  Fly     5 GSGMPSHPPTSTNHHEPPRAPFGAGWVPPMQQNSPYPPPSQPHPHSQPSSQMHPQQHQQYPGGAP 69
            |.|.|:..|:...:.:||:.| |.|       |..|.|..||             |.|.||||.
 Worm    46 GGGYPNQQPSYGGYGQPPQQP-GYG-------NGSYDPYGQP-------------QQQPYPGGG- 88

  Fly    70 APYPPMSAPYPSAAPSYPPYPTSNP------YPAQYAPPAHNHYQQPSVSNSPYPADRGYTPAMT 128
                           ..||||.||.      ||.|              ..:|||...|
 Worm    89 ---------------GQPPYPGSNSNQGGGGYPGQ--------------GGAPYPGGSG------ 118

  Fly   129 AGYDAGYGYGNGQGHGQGHGHGQGHGHGHGQGHEYGHGYGQGYGHGQGHGN---GQGHAHRSLPA 190
             ||.....||...|.|......||......|.:....||.|| |..||.|.   .||:....:
 Worm   119 -GYPQAPQYGFSGGQGSAPQPNQGGYPPQQQQYPPQQGYQQG-GQQQGGGGFFPNQGYGQPVM-- 179

  Fly   191 HREGTPTVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTHFGKDLI 255
              .|||:|.|...|::..||..|||||||.|.:...:|:|:|:|:|.|||||.:.||..:|||||
 Worm   180 --IGTPSVFPVQGFNSNADAEVLRKAMKGLGCNNSKVISILCQRTNWQRQEISKAFKVMYGKDLI 242

  Fly   256 EDIKSETSGNFEKLLVGLLRPIVDYYCAELNDAMAGLGTDEEVLIEILCTLSNMEINTIKNQYLR 320
            :::|.|..|:||.|::.|:.....|...:|:.||.||||.|.|||||:.:.:|.:|..:::.|..
 Worm   243 KELKGELHGDFEDLILALMDAPAIYDAKQLHRAMEGLGTKESVLIEIMTSRTNAQIQQVRDAYKM 307

  Fly   321 LYGAHLESELKSETSGNFKRLLTSLCTAARDESGRVDPVAAKNDARELLKAGELRVGTDESMFNM 385
            |:...||.:|..||||:|||||.|||...||||.:.|.:.|..|||.||:|||.|:|||||.||.
 Worm   308 LFKKDLERDLIGETSGHFKRLLVSLCAGGRDESSQTDGLRANQDARRLLQAGEKRLGTDESTFNA 372

  Fly   386 ILCQRNYQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRLHKAMAG 450
            ||..:|:.||:|:|:||:..:.||:||||:.|||||:.:||:|:...:.|:..|||..||.:|.|
 Worm   373 ILASQNFSQLRLVFEEYQKASNHSIEKAIEFEFSGDIRDGLLAVIAVIRNRPAYFAKLLHDSMKG 437

  Fly   451 IGTNDTQLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALVGEQR 509
            :||.|..|||:.:||:|.||.||:..|:.||..||::.||||.||.||..|.|||...|
 Worm   438 LGTRDNDLIRLCVTRAEYDMGDIRNMFQSLYRTSLENMIKGDCSGAYKEGLIALVNGNR 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AnxB11	NP_001259616.1	Annexin	209..273	CDD:278615	33/63 (52%)
		Annexin	280..345	CDD:278615	30/64 (47%)
		Annexin	364..429	CDD:278615	38/64 (59%)
		Annexin	439..504	CDD:278615	34/64 (53%)
nex-2	NP_001022755.1	Annexin	196..260	CDD:278615	33/63 (52%)
		Annexin	267..332	CDD:278615	30/64 (47%)
		Annexin	350..416	CDD:278615	38/65 (58%)
		Annexin	426..491	CDD:278615	34/64 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	87	1.000	Domainoid score	I5103
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H36149
Inparanoid	1	1.050	347	1.000	Inparanoid score	I1362
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	1	1.000	-	-		otm14773
orthoMCL	1	0.900	-	-		OOG6_100522
Panther	1	1.100	-	-	LDO	PTHR10502
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4028
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	13.010