DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB11 and Anxa1

DIOPT Version :9

Sequence 1:	NP_001259616.1	Gene:	AnxB11 / 32612	FlyBaseID:	FBgn0030749	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_034860.2	Gene:	Anxa1 / 16952	MGIID:	96819	Length:	346	Species:	Mus musculus

Alignment Length:	316	Identity:	120/316 - (37%)
Similarity:	182/316 - (57%)	Gaps:	2/316 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   193 EGTP--TVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTHFGKDLI 255
            :|.|  .|.|..:|:...|...|.||:...|.||..:|:|:.:|:|.|||:|:..:....||.|.
Mouse    29 KGGPGSAVSPYPSFNVSSDVAALHKAIMVKGVDEATIIDILTKRTNAQRQQIKAAYLQENGKPLD 93

  Fly   256 EDIKSETSGNFEKLLVGLLRPIVDYYCAELNDAMAGLGTDEEVLIEILCTLSNMEINTIKNQYLR 320
            |.::...:|:.|::::.:|:....:...||..||.||||||:.|||||.|.||.:|..|...|..
Mouse    94 EVLRKALTGHLEEVVLAMLKTPAQFDADELRGAMKGLGTDEDTLIEILTTRSNEQIREINRVYRE 158

  Fly   321 LYGAHLESELKSETSGNFKRLLTSLCTAARDESGRVDPVAAKNDARELLKAGELRVGTDESMFNM 385
            .....|..::.|:|||:|::.|.:|....|.:...|:...|..|||.|.:|||.|.|||.::|..
Mouse   159 ELKRDLAKDITSDTSGDFRKALLALAKGDRCQDLSVNQDLADTDARALYEAGERRKGTDVNVFTT 223

  Fly   386 ILCQRNYQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRLHKAMAG 450
            ||..|::..|:.:||.|...:.|.:.||:..|..||:.:.|..|.:|.|:...:||.:|::||.|
Mouse   224 ILTSRSFPHLRRVFQNYGKYSQHDMNKALDLELKGDIEKCLTTIVKCATSTPAFFAEKLYEAMKG 288

  Fly   451 IGTNDTQLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALVG 506
            .||....|||::::||||||.:|||.:::.||.||...|..:|.|.|:..|.||.|
Mouse   289 AGTRHKALIRIMVSRSEIDMNEIKVFYQKKYGISLCQAILDETKGDYEKILVALCG 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB11	NP_001259616.1	Annexin	209..273	CDD:278615	21/63 (33%)
		Annexin	280..345	CDD:278615	28/64 (44%)
		Annexin	364..429	CDD:278615	26/64 (41%)
		Annexin	439..504	CDD:278615	29/64 (45%)
Anxa1	NP_034860.2	Annexin 1. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	42..113		22/70 (31%)
		Annexin	47..111	CDD:278615	21/63 (33%)
		Annexin 2. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	114..185		29/70 (41%)
		Annexin	118..183	CDD:278615	28/64 (44%)
		Annexin 3. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	197..269		28/71 (39%)
		Annexin	202..267	CDD:278615	26/64 (41%)
		Annexin 4. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	273..344		31/70 (44%)
		Annexin	277..342	CDD:278615	29/64 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831969
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.760