DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB11 and Anxa8

DIOPT Version :9

Sequence 1:	NP_001259616.1	Gene:	AnxB11 / 32612	FlyBaseID:	FBgn0030749	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_038501.2	Gene:	Anxa8 / 11752	MGIID:	1201374	Length:	327	Species:	Mus musculus

Alignment Length:	316	Identity:	146/316 - (46%)
Similarity:	202/316 - (63%)	Gaps:	2/316 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 REGTPTVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTHFGKDLIE 256
            :||. :|..:::|:...||..|.|||||.||:|.|:|:::.:|||.|||:|.:.||..|||||.|
Mouse    10 QEGV-SVKGSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNVQRQQIAKSFKAQFGKDLTE 73

  Fly   257 DIKSETSGNFEKLLVGLLRPIVDYYCAELNDAMAGLGTDEEVLIEILCTLSNMEINTIKNQYLRL 321
            .:|||.||.||:|:|.|:.|...|...||:|||.||||.|.|:||||.:.:..::..|...|...
Mouse    74 TLKSELSGKFERLIVALMYPPYSYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEED 138

  Fly   322 YGAHLESELKSETSGNFKRLLTSLCTAARDE-SGRVDPVAAKNDARELLKAGELRVGTDESMFNM 385
            ||:.||.:::.:|||..:|:|..|...:||: ||.|||.....||:.|.:|||..:||||..|..
Mouse   139 YGSTLEEDIQGDTSGYLERILVCLLQGSRDDVSGFVDPGLVLQDAQALHEAGEKIMGTDEMKFIT 203

  Fly   386 ILCQRNYQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRLHKAMAG 450
            |||.|:...|..:|:|||.:....:|.:||.|..|.:.|.::.:.:|..|...|||.||:.||.|
Mouse   204 ILCTRSATHLMRVFEEYEKIANKCIEDSIKSETHGSLEEAMLTVVKCTRNVHSYFAERLYYAMKG 268

  Fly   451 IGTNDTQLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALVG 506
            .||.|..|||.|::|||||:..||..|:::|||:|.|.|..||||:||.||..|||
Mouse   269 AGTRDGTLIRNIVSRSEIDLNLIKGQFKKMYGKTLSSMIMADTSGYYKTALLNLVG 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB11	NP_001259616.1	Annexin	209..273	CDD:278615	37/63 (59%)
		Annexin	280..345	CDD:278615	27/64 (42%)
		Annexin	364..429	CDD:278615	26/64 (41%)
		Annexin	439..504	CDD:278615	37/64 (58%)
Anxa8	NP_038501.2	Annexin 1. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	21..92		39/70 (56%)
		Annexin	26..90	CDD:306660	37/63 (59%)
		Annexin 2. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	93..164		29/70 (41%)
		Annexin	97..162	CDD:306660	27/64 (42%)
		Annexin 3. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	177..249		26/71 (37%)
		Annexin	181..247	CDD:306660	26/65 (40%)
		Annexin 4. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	253..324		39/70 (56%)
		Annexin	257..322	CDD:306660	37/64 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831979
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	1	1.000	-	-		mtm8852
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.760