DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB11 and Anxa3

DIOPT Version :9

Sequence 1:	NP_001259616.1	Gene:	AnxB11 / 32612	FlyBaseID:	FBgn0030749	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_038498.2	Gene:	Anxa3 / 11745	MGIID:	1201378	Length:	323	Species:	Mus musculus

Alignment Length:	311	Identity:	131/311 - (42%)
Similarity:	191/311 - (61%)	Gaps:	0/311 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 TVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTHFGKDLIEDIKSE 261
            |:.....|....||..:|||::|.||||..||||:..|||.|||.|.:|::..:.::|.:|:|.:
Mouse    11 TIKDYPGFSPSVDAEAIRKAIRGLGTDEKTLINILTERSNAQRQLIVKQYQAAYEQELKDDLKGD 75

  Fly   262 TSGNFEKLLVGLLRPIVDYYCAELNDAMAGLGTDEEVLIEILCTLSNMEINTIKNQYLRLYGAHL 326
            .||:||.::|.|:.....:...:|..:|.|.||||:.|||||.|.|:.::..|...|..:|...|
Mouse    76 LSGHFEHVMVALVTAPALFDAKQLKKSMKGTGTDEDALIEILTTRSSRQMKEISQAYYTVYKKSL 140

  Fly   327 ESELKSETSGNFKRLLTSLCTAARDESGRVDPVAAKNDARELLKAGELRVGTDESMFNMILCQRN 391
            ..::.|||||:|::.|.:|....||||.:||...||.||:.|..|||.:.||||..|..:||.|:
Mouse   141 GDDISSETSGDFRKALLTLADGRRDESLKVDEHLAKKDAQILYNAGENKWGTDEDKFTEVLCLRS 205

  Fly   392 YQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRLHKAMAGIGTNDT 456
            :.||||.|.||..::...:|.:||.|.||...:.|:||..|..|...:.|.|||:|:.|.||::.
Mouse   206 FPQLKLTFDEYRNISQKDIEDSIKGELSGHFEDLLLAIVHCARNTPAFLAERLHQALKGAGTDEF 270

  Fly   457 QLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALVGE 507
            .|.|::::|||||:.||:..|::.||.||.|.|:.||||.|:..|..:.||
Mouse   271 TLNRIMVSRSEIDLLDIRHEFKKHYGYSLYSAIQSDTSGDYRTVLLKICGE 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB11	NP_001259616.1	Annexin	209..273	CDD:278615	30/63 (48%)
		Annexin	280..345	CDD:278615	25/64 (39%)
		Annexin	364..429	CDD:278615	28/64 (44%)
		Annexin	439..504	CDD:278615	30/64 (47%)
Anxa3	NP_038498.2	Annexin 1. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	18..89		32/70 (46%)
		Annexin	23..87	CDD:395139	30/63 (48%)
		Annexin 2. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	90..161		26/70 (37%)
		Annexin	94..159	CDD:395139	25/64 (39%)
		Annexin 3. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	173..245		32/71 (45%)
		Annexin	178..243	CDD:395139	28/64 (44%)
		Annexin 4. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	249..320		31/70 (44%)
		Annexin	255..318	CDD:395139	30/62 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831975
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	1	1.000	-	-		mtm8852
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.760