DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31102 and CG31288

DIOPT Version :9

Sequence 1:	NP_001262951.1	Gene:	CG31102 / 326118	FlyBaseID:	FBgn0051102	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_733094.1	Gene:	CG31288 / 318664	FlyBaseID:	FBgn0051288	Length:	428	Species:	Drosophila melanogaster

Alignment Length:	427	Identity:	173/427 - (40%)
Similarity:	269/427 - (62%)	Gaps:	11/427 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPDNSNKFSASSDVRIPAWINEAYFKRLLKREFREFRRILNLSIIPATPPGETYTSLLMRIVIDI 65
            |.||.:..:.:..:.||.||||.||:.:|.::..:..::|..:::.|.||||.:||.::|:.|.:
  Fly     1 MSDNDDIVNPNEHLIIPDWINEKYFESVLAKDEPDHVKVLKFTVVAAIPPGENFTSTMLRVYIKL 65

  Fly    66 ELKDGFSQQKSYIVKTMLDDAQGNGGFVNTLNIFPKEKMMYETIIPNLEQLYEEAGLSVKFAPKC 130
            |:|||..:.|:||.||||.:.:| |..:|...:||||.|||:|.:|..|.||::.|..::.||||
  Fly    66 EMKDGSVKTKTYIFKTMLPEERG-GSDINEFGLFPKEAMMYKTYLPAFEALYKDVGWDIQLAPKC 129

  Fly   131 HHAEDIKGRICLVQEDLQTKKYRNINRLKGFDMAHMHRVLEKLAEFHAAGAVWRQRKGPFPDDFQ 195
            .|.|:.:|.|..:.|||..|:::|::|.||.||.||.:.|:||||:|||.||:.:..||:|.:|.
  Fly   130 LHTEEREGDIHFIFEDLCVKRFKNMDRTKGLDMEHMTKCLQKLAEYHAASAVYEELHGPYPSEFS 194

  Fly   196 RIYLPANYQK--SKSYQARLQSYKTAIASWGLADHEQYVSRIPTADQFVQSYASCFNN---NPQE 255
            ..::..:.:|  ...:|.:.::||.|:.||||.|.::|:...||..|:   :|.|.:.   ||.|
  Fly   195 EGFVKKDVKKFHVDGFQLKEKAYKKAMLSWGLKDADKYIKAFPTVKQY---WAQCLSTLELNPDE 256

  Fly   256 FKVLNHGDFWSSNIMLSYTQTGDINQVRFVDFQLCKWGSPAQDLWELIICSARHSIRIQYFDYFI 320
            |.|||||||||||:|.||...|.:.::..:|||:..|||||.||...:..|..:.:||:.||:|:
  Fly   257 FHVLNHGDFWSSNLMSSYLPDGTLEKLILIDFQIVMWGSPAMDLLFFLTLSPTNDLRIKEFDHFV 321

  Fly   321 RIYHTHLVRCLKILKYSERIPMLRELHMSM--IKYGFWGYFTTFTHLVFILLPPDTEASLVKLTQ 383
            |||...||.|||:||..:.:|.||:|..||  ..:.|:.:|:...||..||.|.|.::::..|:.
  Fly   322 RIYWERLVECLKVLKLKKPLPKLRDLQNSMNNKNHSFYAFFSILNHLPIILFPTDKDSNIHNLSA 386

  Fly   384 PGEEGDRFRSKVYTNPLYVRSALSIFPFLLRRGILDF 420
            ..|||:.:|.::.:||.:......::|||..||||:|
  Fly   387 NTEEGENYRLRLLSNPAFGNVMKDLYPFLYNRGILNF 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31102	NP_001262951.1	EcKinase	50..336	CDD:281023	128/290 (44%)
CG31288	NP_733094.1	EcKinase	50..331	CDD:281023	124/284 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442474
Domainoid	1	1.000	207	1.000	Domainoid score	I6156
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I6344
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.910