DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31099 and CG6908

DIOPT Version :9

Sequence 1:	NP_733099.1	Gene:	CG31099 / 326117	FlyBaseID:	FBgn0051099	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_650105.1	Gene:	CG6908 / 41410	FlyBaseID:	FBgn0037936	Length:	449	Species:	Drosophila melanogaster

Alignment Length:	412	Identity:	124/412 - (30%)
Similarity:	211/412 - (51%)	Gaps:	31/412 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VPKIPDWVSSLSLNQAVHSVLEDGVQITSVIPSVHLIQFRN-----CTVLLPIQVKVQLRDFTMK 62
            :..||.|:.    .|....:||........|.|..|.....     .|:||....:::|.|.:.:
  Fly    44 IEPIPAWLD----QQKFEPILERDFPDLKKIKSFRLEPTAGKGENYTTLLLRANFELELNDGSEQ 104

  Fly    63 KLFFLLKAQHGTDIQAMVMNQLKMFQREHQVYHNVLPKLEEIYREVGKKVSFGPRAFRLDYSIGV 127
            .:.::.|....:..:..|.: .|:|.:|...|...:|:.|::|::.|||:|||||.:.....:..
  Fly   105 SISYMAKILPNSGNRENVAS-WKVFYKERNTYGQYIPEFEQMYKDAGKKISFGPRYYESQIELDD 168

  Fly   128 QYVLLEDLKAKSYKNVERQAGFNKLCLKQVLKKLAQFHAASAVCVEKHGAFSNLLVNGVYTKANE 192
            :.::||||..:.::||:||.|.:....:..|:|||||||||||..|..|::..     .|.:...
  Fly   169 ELIVLEDLGKRGFRNVDRQNGLDIQHTEATLEKLAQFHAASAVRFELKGSYPE-----EYNQNLC 228

  Fly   193 SVLQELNDPEIFLSQLRRW----RLGDHFH-KRLVEKEKDLVDGLLKLHSPD-SNEFNVLNHSDC 251
            ||:..|.  |:..:||:.:    .|.|..| ...|:......|.:.:..:|. ..||.||||.|.
  Fly   229 SVVDSLK--ELRENQLKAYIDAFPLYDASHLTNDVQAYGSQADDMFQSFAPKIEGEFRVLNHGDA 291

  Fly   252 WVNNVMFKFDDSGHVEDTALLDYQLVKYGSPAIDLYYTILSSAEKDIKLAQFDNMVQYYFYHLLD 316
            |.||:|:::|::|.:.:...:|.|:.::.|||.||.|.||||.|.|||:|:||.::::|...|::
  Fly   292 WCNNIMYQYDEAGKLAEVNFVDLQMSRFSSPAQDLLYLILSSTELDIKIAKFDYLIKFYHEKLIE 356

  Fly   317 NLKALNFGGSLPQLQHIRDALNKNGLAAYVVVTRALPITMMNQFEDEVN-------ERYASKMKC 374
            :||.|.:...||.|:.:..::...|.....:|:..||:.:::. .|:.|       |....|::.
  Fly   357 SLKLLKYPKPLPSLRSLHQSIFIYGDWILPIVSILLPLVLIDG-GDDANMDSLMDGEGAGDKIRN 420

  Fly   375 AMFTSRKYIQAIKDILPWMEER 396
            .||.:.:.|:..|:||||...|
  Fly   421 NMFKNHRVIKHQKEILPWAHRR 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31099	NP_733099.1	EcKinase	44..323	CDD:281023	95/284 (33%)
CG6908	NP_650105.1	EcKinase	81..363	CDD:281023	95/289 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442553
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I6344
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26787
OrthoDB	1	1.010	-	-		D101022at50557
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	7.010