DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tau and zgc:158260

DIOPT Version :9

Sequence 1:	NP_733224.2	Gene:	tau / 326116	FlyBaseID:	FBgn0266579	Length:	717	Species:	Drosophila melanogaster
Sequence 2:	NP_001073522.1	Gene:	zgc:158260 / 571389	ZFINID:	ZDB-GENE-061201-24	Length:	364	Species:	Danio rerio

Alignment Length:	300	Identity:	61/300 - (20%)
Similarity:	100/300 - (33%)	Gaps:	93/300 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   353 QLQQQQQQQQQ----QQHMQQQQQLRPLSAASAHNNNDDDDDVVMGP-AVTPLKTFNSRPDPMGE 412
            :||:::..:.|    :|::|.|.|...:.|.        :..:...| |:.|.......|: :.|
Zfish    80 KLQRKKLSKNQVCYSKQNLQSQTQREFIDAV--------EHKLKQHPLALYPHLESGMIPE-LFE 135

  Fly   413 PLLEDIEPPFQTSPPAGESKKGPGFKGDNDSGVDESTQEKDRNGPNSPSSPVKTPTSTSSKPDKS 477
            .:|..::|..........:||......|..:..:.||||           .:|..||..|..|:|
Zfish   136 QVLSVLDPDMCMKGELSLTKKTEKHLEDRRAKCEVSTQE-----------ILKRSTSIKSPKDES 189

  Fly   478 GTSRPPSATPSNKSAPKSRSASKNRLLLKTPEPEPVKKVPMNKVQVGHAPSPN------LKAVRS 536
            ..:|..:|                   .|..|.:.:.|    :.|..:|....      :|....
Zfish   190 KDTRARNA-------------------YKWQELKEIDK----EYQTANAKQSQEDKQMFVKFFCE 231

  Fly   537 KIGSLDNATYKPGGGHVKIESKKIDIKAAPRIEAKNDKYMPKGGEKKIVTTKLQWNAKSKIGSLE 601
            .|.||        ||...      |::.:..::.....|     |||...|.          .:.
Zfish   232 WITSL--------GGETS------DLRESTILDLFKSDY-----EKKTTLTL----------PIN 267

  Fly   602 NAAHKPGGGDKKIETLKMDFKDKA--------KPKVGSTA 633
            ..||:|.|  |...::|..|||..        |||:..||
Zfish   268 KIAHQPSG--KCHSSVKEHFKDHCVKELTEAYKPKILKTA 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tau	NP_733224.2	Tubulin-binding	521..551	CDD:278828	6/35 (17%)
		Tubulin-binding	583..610	CDD:278828	5/26 (19%)
		Tubulin-binding	613..642	CDD:278828	8/28 (29%)
		Tubulin-binding	644..672	CDD:278828
zgc:158260	NP_001073522.1	FAM47	31..>144	CDD:291315	14/72 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595927
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930