Protein Alignment tau and maptb

DIOPT Version :9

• Sequence 1: NP_733224.2
• Gene: tau / 326116
• FlyBaseID: FBgn0266579
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: XP_021329127.1
• Gene: maptb / 567833
• ZFINID: ZDB-GENE-081027-2
• Length: 752
• Species: Danio rerio
• Alignment Length: 841
• Identity: 175/841 - (20%)
• Similarity: 288/841 - (34%)
• Gaps: 308/841 - (36%)

  Fly     9 SGQEIISPQDYPVQQQRAQSKSEYVMNSASVDRPQQQSRPQPTQDYVPFESSDSSVERKKEQPSA 73
            :|:|.::|.. |.:..|:        ::||||...::...:......|.||..|
Zfish    85 AGEEALTPGS-PPKSGRS--------SAASVDGEGERENGERESSVSPRESPVS----------- 129

  Fly    74 QLSTDYTNSNTTSDSASYGSDSVSKQQIRSQQNPEYQNNAYEAPRDDRSQLQPQRSQPATDYSAY 138
                .:....|.:|..|.|......|..||..:....:::.....::..:::..
Zfish   130 ----PHPLPVTLADGLSSGITGFDSQMKRSPSDKMSDHHSPSGSEEEEHEMEKS----------- 179

  Fly   139 ERQQRPPPTTLDYTTGYNAPPKDRTTLSRTNSRPTLSSPNPKLQSIPNTEYVRPPQNFVLPPQMR 203
            ||:....|       |:.|.|:....|....:.      :.::..:.:.|..:...:.|
Zfish   180 ERRFSGSP-------GFGADPRSTINLKENENE------DKEVSEVSDEEEEQTGVSLV------ 225

  Fly   204 PAVGPPQPRPPFAGARPMVGMGPRPPMPPNMAARPPPLRSTDSKSNLLMGPPMRPGMPPQLNMQQ 268
                                   ...:.|::..:......|          |:...|.|    ::
Zfish   226 -----------------------SSSITPDLTTQKEDEHET----------PIHLPMTP----EE 253

  Fly   269 ARLPNAGGQLSPPGQGPPRPPGGFPWNPAGAPGMPPGARPPQNMTRPPPPTFARPPPGQPLQAPF 333
            |:........:.| |.|..|.|...|. ..:...||.::.|.:         .|..||.||..
Zfish   254 AKKRGLSFDYTEP-QDPGHPHGPVGWE-CSSDKTPPESKSPDS---------CRADPGSPLTP-- 305

  Fly   334 NRPPFNQPPMQPQQQQPPQQLQQQQQQQQQQQHMQQQQQ----LRPLS----------AASAHNN 384
                 :....|.|::...:..|...|:::::..:.:|::    :.|.|          .|..|.:
Zfish   306 -----SAAADQTQEESSLRDFQTDTQEEEEEIEVPEQEEEETPVPPFSREVATPKMELKAEEHLD 365

  Fly   385 ND--------------DDDDV---------------------------VMGPAVT---------- 398
            ::              |||:|                           ::.|.||
Zfish   366 SNKTKEVSQEKYLETSDDDEVETEKVKSVATPEPVVIPENAAIPEPVAILEPVVTKAKDAVKPSA 430

  Fly   399 ------------------------PLKTFNSRPDPMGEPLLE-----DIEPPFQTSPPAGESKKG 434
                                    |:.|.::.|.|...|.|:     |..|..:.|.|: ::|.|
Zfish   431 EVPPTKPPSKAALVKEAPAKKTKKPVATVSATPSPKTAPSLQKTPSKDAAPARKASVPS-KAKAG 494

  Fly   435 PGFKGDNDSGVDESTQ-------------------EKDRNGPNS---PSSPVKTPTSTSSKPDKS 477
            .|...:..:| |..|:                   |:.|.||.|   ..|| ||       ||:|
Zfish   495 AGATPEKKAG-DAKTKTAGAKPQGVGAKIPAASRMEQRRTGPGSIERADSP-KT-------PDRS 550

  Fly   478 GTSRPP--SATPSN--------KSAPKSRSASKNRLLLKTPEPEPVKKVPMNKVQVGHAPSPNLK 532
            |.|.|.  |:||..        ::.|||..:.::|..:     .||            ||.|:||
Zfish   551 GCSSPASRSSTPGQQVKKVAVVRTPPKSPGSLRSRAQI-----APV------------APMPDLK 598

  Fly   533 AVRSKIGSLDNATYKPGGGHVKIESKKIDIKAAPRIEAKNDKYMPKGGEKKIVTTKLQWNAKSKI 597
            .|:|||||.:|..::||||.::|..||||:.                            |.:||.
Zfish   599 NVKSKIGSTENLKHQPGGGKIQIVHKKIDLS----------------------------NVQSKC 635

  Fly   598 GSLENAAHKPGGGDKKIETLKMDFKDKAKPKVGSTANVKHQPGGGDIKIQTQKLEIKAQSKVGS- 661
            ||..|..||||||:.:|::.|:||  ||:.||||..|:.|.||||..:|::.||..:.|:|..:
Zfish   636 GSKANIHHKPGGGNVEIKSEKLDF--KAQSKVGSLENIGHVPGGGQRRIESHKLNFRDQAKARTD 698

  Fly   662 --LDNVKHKP----GGGEKKIFDDKDYLKNVEHSVALTTPPTQSPLPSMTASGADENLNQQ 716
              .|.|...|    .|..::       |.||..|.:|..  |.||..|..|.....:|.:|
Zfish   699 HGADIVCKSPDISTDGSPRR-------LSNVSSSGSLNM--TDSPQLSTLADQVSASLAKQ 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tau	NP_733224.2	Tubulin-binding	521..551	CDD:278828	14/29 (48%)
		Tubulin-binding	583..610	CDD:278828	10/26 (38%)
		Tubulin-binding	613..642	CDD:278828	14/28 (50%)
		Tubulin-binding	644..672	CDD:278828	8/34 (24%)
maptb	XP_021329127.1	Atrophin-1	<266..581	CDD:331285	67/342 (20%)
		Tubulin-binding	<596..617	CDD:306842	11/20 (55%)
		Tubulin-binding	619..648	CDD:306842	15/56 (27%)
		Tubulin-binding	650..678	CDD:306842	14/29 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	1.000	Domainoid score	I12007
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005553
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4510
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.000