Protein Alignment tau and ptl-1

DIOPT Version :9

• Sequence 1: NP_733224.2
• Gene: tau / 326116
• FlyBaseID: FBgn0266579
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001367353.1
• Gene: ptl-1 / 175230
• WormBaseID: WBGene00004212
• Length: 458
• Species: Caenorhabditis elegans
• Alignment Length: 508
• Identity: 139/508 - (27%)
• Similarity: 218/508 - (42%)
• Gaps: 149/508 - (29%)

  Fly   279 SPPGQGPPRP------------PGGFP---WNPAGAPGMPPGARP-PQNMTRPPPPTFARP---P 324
            |.||..|..|            .|.||   ..|...|...|...| |:....|.|....:|   |
 Worm     6 SEPGSEPGSPGENENSMETQYSQGSFPEVAVEPEPEPEPEPEPEPEPEPEPEPEPEPKPKPEVEP 70

  Fly   325 PGQPLQAPFNRP-PFNQPPMQPQQQQPPQQLQQQQQQQQQQQHMQQQQQLRPLSAASAHNNNDDD 388
            ..||...|..:| |..:|.::|:.:..|....:.:.:.:.:..:::::::
 Worm    71 VPQPEPEPEYQPEPEPEPEVEPEPEPEPVPEPEPEPEPEPEPVVEKEEEV--------------- 120

  Fly   389 DDVVMGP--AVTPLKTFNSRP-DPMGE-PLLEDIEPPFQTSPPAGESKKGPGFKGDNDSGVD--- 446
              ||..|  ...|.|:..|:| .|:.: |.:|||.|....|....|:      .|.:|...|
 Worm   121 --VVESPPREQEPEKSGKSKPSSPIPDAPTMEDIAPRELESLNFSET------SGTSDQQADRIM 177

  Fly   447 -----ESTQEKDRNGPNSPSSP---------VKTPTS--TSSKPDKSGTSRPPSATPSNK---SA 492
                 |..:||.:..| :||.|         ::.||:  ...||..:...||.:||||::   |.
 Worm   178 QNNENERVEEKKQMSP-TPSQPQHKTPQRSGIRPPTAILRQPKPIPASLPRPATATPSSQRAIST 241

  Fly   493 PKSRSASKNRLLLKTPEPEPVKKVPMNKVQVGHAPS-----------PNLKA----VRSKIGSLD 542
            |:..:::       .|.|.|:.|:...:..|..:.|           |.:.|    |:||:||:.
 Worm   242 PRQTAST-------APSPRPISKMSRERSDVQKSTSTRSIDNVGRMTPKVNAKFVNVKSKVGSVT 299

  Fly   543 NATYKPGGGHVKIESKKIDIKAAPRIEAKNDKYMPKGGEKKIVTTKLQWNAKSKIGSLENAAHKP 607
            |  :|.|||:|:|.|                       ||::      :||:||:|||:||.|..
 Worm   300 N--HKAGGGNVEIFS-----------------------EKRL------YNAQSKVGSLKNATHVA 333

  Fly   608 GGGDKKIETLKMDFKDKAKPKVGSTANVKHQPGGGDIKIQTQKLEIKAQSKVGSLDNVKHKPGGG 672
            |||:.:||..|:|| ..|.|||||..|  :||...|:||.::||..:|:|||||:||..|||.||
 Worm   334 GGGNVQIENRKLDF-SAASPKVGSKTN--YQPAKSDVKIVSEKLTWQAKSKVGSMDNAAHKPAGG 395

  Fly   673 EKKIFDDKDYLKNVEHSVALTTPPTQSPLPSMTASGAD--------ENLNQQS 717
            ..::         :...||::.|      ..|||:..|        ::::|:|
 Worm   396 NVQV---------ISSEVAVSRP------KMMTATIIDKKKDFAKRQSVSQRS 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tau	NP_733224.2	Tubulin-binding	521..551	CDD:278828	12/44 (27%)
		Tubulin-binding	583..610	CDD:278828	11/26 (42%)
		Tubulin-binding	613..642	CDD:278828	14/28 (50%)
		Tubulin-binding	644..672	CDD:278828	15/27 (56%)
ptl-1	NP_001367353.1	MAP65_ASE1	<176..269	CDD:397896	24/100 (24%)
		Tubulin-binding	308..337	CDD:395337	17/57 (30%)
		Tubulin-binding	367..396	CDD:395337	16/28 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I7949
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I3194
Isobase	1	0.950	-	0	Normalized mean entropy	S5326
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005553
OrthoInspector	1	1.000	-	-		oto20121
orthoMCL	1	0.900	-	-		OOG6_106583
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8371
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.840