DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tau and LOC100909677

DIOPT Version :9

Sequence 1:	NP_733224.2	Gene:	tau / 326116	FlyBaseID:	FBgn0266579	Length:	717	Species:	Drosophila melanogaster
Sequence 2:	XP_003752094.1	Gene:	LOC100909677 / 100909677	RGDID:	6502369	Length:	396	Species:	Rattus norvegicus

Alignment Length:	401	Identity:	73/401 - (18%)
Similarity:	141/401 - (35%)	Gaps:	114/401 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   335 RPPFNQPPMQPQQQQPPQQLQQQQQQQQQQQHMQQ--QQQLRPLSAASAHNNNDDDDDVVMGP-- 395
            |.|.||||..|..:...:...:|......:.|.||  |::|...:     ...:..::::.|.
  Rat     5 RMPENQPPQLPSYKHVLKHKTEQLSSPFMENHYQQFSQEKLGDFT-----RYYEPHEEILSGTIR 64

  Fly   396 -AVTPLKTFNSRPDPMGEPLLEDIEPPFQTSPPAGESKKG---PGFKGDNDSGVDESTQEKDRNG 456
             .|.| :..:..|..:.:.....::..|:........::|   ..:|.|:.|..::..:|...|.
  Rat    65 GTVFP-RISHKVPSTLTKMNQRKLQQDFRMFCSISIGQQGIRRTQYKWDHLSQTEDDAKEYVINL 128

  Fly   457 PNSP------------SSPVKTPTSTSSKPDKSGTS---RPPSATPSNKSAPKSRSASKNRLLLK 506
            ...|            .:.:|     ::|.:|.|.:   :.....|.|     ||...||.|...
  Rat   129 KEQPKCDQNLNKWYCFENQIK-----ANKNNKQGENIHKKLNLRLPGN-----SRLGQKNFLPAY 183

  Fly   507 TPEPEPVKKVPMNKVQVGHAP--SPNLKAVRSKIGSLDNATYKPGGGHVKIESKKIDIKAAPRIE 569
            |...:.:    ::.:...:|.  |.|:......:|:||           ..:...:|....|..:
  Rat   184 TFRNQNL----LDSLSCRYAQGGSDNIYDWNEALGNLD-----------VFQQFDMDYANQPTYD 233

  Fly   570 AKNDK---YMP------KG--GEKKIVTTKLQWNAKSKIGSLENAAHKPGGGDKKIETLKMDFKD 623
            ..:||   ::|      :|  .||.|..:|.....::|:.:..|              |.|..|:
  Rat   234 EFSDKIISHLPSKLKYFRGLTKEKGIKFSKQISKFETKVQNQHN--------------LSMSTKE 284

  Fly   624 KAKPKVGSTANVKHQPGGGDIKIQTQKL-EIKAQSKVGSLDNVKHKPGGGEKKIFD-------DK 680
            |          .|::|       ..||| ::|.|:        ..:|..|.|.:.:       :.
  Rat   285 K----------FKYEP-------SYQKLKQLKTQA--------VRQPLNGSKNLLEIEGKSICEP 324

  Fly   681 DYLKNVEHSVA 691
            |.|:|:..::|
  Rat   325 DLLENLYGAIA 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tau	NP_733224.2	Tubulin-binding	521..551	CDD:278828	6/31 (19%)
		Tubulin-binding	583..610	CDD:278828	4/26 (15%)
		Tubulin-binding	613..642	CDD:278828	6/28 (21%)
		Tubulin-binding	644..672	CDD:278828	6/28 (21%)
LOC100909677	XP_003752094.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342108
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930