Protein Alignment tau and LOC100001114

DIOPT Version :10

• Sequence 1: NP_733224.2
• Gene: tau / 326116
• FlyBaseID: FBgn0266579
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: XP_005162978.3
• Gene: LOC100001114 / 100001114
• -ID: -
• Length: 1237
• Species: Danio rerio
• Alignment Length: 775
• Identity: 189/775 - (24%)
• Similarity: 293/775 - (37%)
• Gaps: 229/775 - (29%)

  Fly     4 TGKDRSGQEIISPQD--YPVQQQRAQSKSEYVMNSASVDRPQQ-QSRPQPTQDYVPFESSDSSVE 65
            |.||:. .|.|:.:|  .|.|..:|:       |:..:|:.:: :.:...|..:|........:|
Zfish   599 TEKDQK-METITEKDKSEPKQTTKAE-------NTEPLDKNKEVEKKTDETVHHVETPVKVEKIE 655

  Fly    66 R-----KKEQPSAQL---STD-YTNSNTTSDSASYGSDSVSKQQI---------RSQQNPEYQNN 112
            :     |.|...|.:   ||| ...:..|::.:|...:.|.||::         :|:|..:.:..
Zfish   656 KVERSTKDETEKAAMVEKSTDLIEKTEKTAEFSSKKEEPVEKQELKKEEVKVENKSEQKDDVKEK 720

  Fly   113 AYEAPRDDRSQLQ-----PQRSQPA---------TDYSAYERQQRPPPTTLDYTTGYNAPPKDRT 163
            |.:..:.|:::.:     .::|:||         .|..|.:...:|.......|.|  ||.||
Zfish   721 AEQKTQQDKTEEEKVEEKAEKSEPADKKPAKAETKDDKAKKAAAKPSAAKPALTNG--APGKD-- 781

  Fly   164 TLSRTNSRPTLSSPNPKLQSIPNTEYVRPPQNFVLPPQMRPAVGPPQPRPPFAGARPMVGMGPRP 228
                      ||||..|.:                               |.||........|||
Zfish   782 ----------LSSPEKKTK-------------------------------PVAGLSKPSSAKPRP 805

  Fly   229 PMPPNMAARPPPLRSTDSKSNLLMGPPMRPGMPPQLNMQQARLPNAGGQLSPPGQGPPRP----- 288
            .......|.|....:|.:.|    ||                        :|..:..|.|
Zfish   806 SSASTATAAPKRPTATSASS----GP------------------------APISKKAPAPKTSAA 842

  Fly   289 PGGFPWNPAGAPGMPPGARPPQNMTRPPPPTFARPPPGQPLQAPFNRPPFNQP--PMQPQQQQPP 351
            |.|.. .||.|...||.|.......:|...|..||...:|..|| :||..::|  ..:|....|.
Zfish   843 PAGTK-RPATATARPPTATTAARDVKPKTLTEKRPLVPKPSTAP-SRPAADKPASTTRPTASAPA 905

  Fly   352 QQLQQQQQQQQQQQHMQQQQQLRPLSAASAHNNNDDDDDVVMGPAVTP---LKTFNSRPDPMGEP 413
            .:                    |||:|.:.....||.....:...||.   .|...:||...|..
Zfish   906 AR--------------------RPLAAKAESKPADDKKASTLKTTVTDGARSKPATARPSTSGTI 950

  Fly   414 LLEDIEPPFQTSPP-AGESKKGPGFKGDNDSGVDESTQEKDR--NGPNSP------SSPVKTPTS 469
            .......|..|..| ||    |.|           :|.|..|  ..|..|      :|...|..|
Zfish   951 SSSASTRPRPTKTPLAG----GTG-----------TTPEVPRIQTMPRPPRQSIFSTSTTNTTRS 1000

  Fly   470 TSSKPDKSGTSRPPSATPSNKSAPKSRSASKNRLLLKTPEPEPVKKVPMNKVQVGHAPSPNLKAV 534
            |:.....:.|:|..|::.::.:.|.|.:|                              |::|.:
Zfish  1001 TARTTTTTSTTRITSSSTASTARPSSTAA------------------------------PDVKNI 1035

  Fly   535 RSKIGSLDNATYKPGGGHVKIESKKIDIKAAPRIEAKNDKYMPKGGEKKIVTTKLQW-NAKSKIG 598
            ||||||.||..::||||.|.....:.|.:.:...|:..       |:.:||:.|:.: :..|::|
Zfish  1036 RSKIGSTDNIKHQPGGGKVSGSQSRTDSQISASKESSQ-------GKVQIVSKKVDYSHVTSRLG 1093

  Fly   599 SLENAAHKPGGGDKKIETLKMDFKDKAKPKVGSTANVKHQPGGGDIKIQTQKLEI--KAQSKVGS 661
            |.:|..|.||||:.:|.:.|:|. .|...|.||.:|:||:||||::||::.|:..  ||||||||
Zfish  1094 SKDNMKHIPGGGNVQILSKKIDL-SKVTSKCGSKSNIKHKPGGGEVKIESHKVNYKDKAQSKVGS 1157

  Fly   662 LDNVKHKPGGGEKKIFDDK-DYLKN----VEHSVALTTPPTQSPLPSMTASGADENLNQQ 716
            :|||.|:||||:.||...| ::.:|    .:|...:...|.           :|||..||
Zfish  1158 MDNVNHEPGGGKIKIESFKLNFRENARSRTDHGADIIEWPV-----------SDENPVQQ 1206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tau	NP_733224.2	PHA03247	<113..529	CDD:223021	88/448 (20%)
		Tubulin-binding	521..551	CDD:459807	12/29 (41%)
		Tubulin-binding	582..610	CDD:459807	10/28 (36%)
		Tubulin-binding	612..642	CDD:459807	12/29 (41%)
		Tubulin-binding	644..672	CDD:459807	17/29 (59%)
LOC100001114	XP_005162978.3	None