DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tau and mapta

DIOPT Version :9

Sequence 1:NP_733224.2 Gene:tau / 326116 FlyBaseID:FBgn0266579 Length:717 Species:Drosophila melanogaster
Sequence 2:XP_021335889.1 Gene:mapta / 100000342 ZFINID:ZDB-GENE-081027-1 Length:403 Species:Danio rerio


Alignment Length:420 Identity:120/420 - (28%)
Similarity:184/420 - (43%) Gaps:114/420 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   367 MQQQQQLRPLSAASAHNNNDDD----------------DDVVMGPAVTPLKTF--NSRPDPMGEP 413
            |.|...|.. |:.:||.|:.|:                ::.::.|...|:|..  :||.|...:|
Zfish     1 MDQHHDLLS-SSPNAHYNSGDNMASSLSGMTINDHHHKENGLVRPGDCPMKESPEDSRGDETEDP 64

  Fly   414 LLE-----DIEPPFQTSPPAGESKKGPGFKGDNDSGV------------DESTQEKDRNGPNSPS 461
            ..|     .:.|..|:.......|:.|.....:.:|.            .::.:....:.|.:|.
Zfish    65 GAEVASAGGMAPTAQSKTNGDAEKRAPSSSRPHAAGTKIPAMTAVAKNGKDTAENSGHSSPGTPK 129

  Fly   462 SPVK-----TPTSTSSKPDKSGTSRPPSATPSNKSAPKSRSASKNRLLLKTPEPEPVKKVPMNKV 521
            ||..     .|.||.::..|....|....:|.|:| |.|.||:                      
Zfish   130 SPASKAAGGKPPSTGNEIKKVAVIRSTPKSPKNRS-PTSLSAA---------------------- 171

  Fly   522 QVGHAPSPNLKAVRSKIGSLDNATYKPGGGHVKIESKKIDIKAAPRIEAK-----NDKYMPKGGE 581
                ||.|:||.||||:||.||..::||||.::|..:|:|..   .:::|     |.|:.|.||.
Zfish   172 ----APLPDLKNVRSKVGSTDNLKHQPGGGRIQILDQKVDFS---NVQSKCGSKANLKHTPGGGN 229

  Fly   582 KKIVTTKLQW-NAKSKIGSLENAAHKPGGGDKKIETLKMDF---------KDKAK---------- 626
            .||:..|:.: ..:||.||.:|..|.||||:.:|...|:|.         ||..|          
Zfish   230 VKILDQKVDFTKVQSKCGSKDNIKHAPGGGNVQILDQKLDLTNVQARCGSKDNLKHVPGGGKVQI 294

  Fly   627 -----------PKVGSTANVKHQPGGGDIKIQTQKLEIKAQSKVGSLDNVKHKPGGGEKKIFDDK 680
                       .|.||..|::|:||||:|:|:::||:.|||||:||:||:||.||||.::  .:|
Zfish   295 LHKKIDLSNVQSKCGSKDNLRHKPGGGNIEIRSEKLDFKAQSKIGSMDNIKHTPGGGNRR--REK 357

  Fly   681 DYLKNVEHSVALTTP-PTQSPLPSMTASGA 709
            |...|........|| |:::|    |.|.|
Zfish   358 DRGANTPQDEGFLTPDPSETP----TLSSA 383

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tauNP_733224.2 Tubulin-binding 521..551 CDD:278828 15/29 (52%)
Tubulin-binding 583..610 CDD:278828 11/27 (41%)
Tubulin-binding 613..642 CDD:278828 13/58 (22%)
Tubulin-binding 644..672 CDD:278828 17/27 (63%)
maptaXP_021335889.1 DUF4045 <44..>167 CDD:330572 26/123 (21%)
Tubulin-binding <176..197 CDD:306842 12/20 (60%)
Tubulin-binding 199..228 CDD:306842 7/31 (23%)
Tubulin-binding 230..259 CDD:306842 11/28 (39%)
Tubulin-binding 261..290 CDD:306842 6/28 (21%)
Tubulin-binding 292..321 CDD:306842 7/28 (25%)
Tubulin-binding 323..351 CDD:306842 17/27 (63%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 47 1.000 Domainoid score I12007
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0005553
OrthoInspector 1 1.000 - - otm24625
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X4510
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
65.910

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