DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atg16 and AT4G38480

DIOPT Version :9

Sequence 1:	NP_001138124.2	Gene:	Atg16 / 326115	FlyBaseID:	FBgn0039705	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_568042.1	Gene:	AT4G38480 / 830004	AraportID:	AT4G38480	Length:	471	Species:	Arabidopsis thaliana

Alignment Length:	405	Identity:	92/405 - (22%)
Similarity:	146/405 - (36%)	Gaps:	113/405 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   265 DEAAINGAMEAIGLDDNEYISARFTAGEIAENSRASIDTLKATGYLGQANPTKILMKFEAHENES 329
            |.:.:|.....:||..|...|.||:|.|         |.|:..|         :..|.:.|:...
plant    12 DHSVVNVWERELGLLPNRSFSNRFSASE---------DLLRRLG---------LDKKLDKHKGCV 58

  Fly   330 HAVRWSPVERMVATGGADRKVKLWDIGKNSTEPRAVLSGSSAGINSVDFDSTGAYILGTSNDYGA 394
            :.|.::....::.:|..||:|.|||....|.:    ||..|...|:: |.   |..:..|:| ..
plant    59 NTVSFNADGDILLSGSDDRQVILWDWQTASVK----LSFDSGHFNNI-FQ---AKFMPFSDD-RT 114

  Fly   395 RVWTVMDNRLRHTLTGHSGKVMAA----------KYVQE---PIKVVTGSHDRTLKIWDLRS--- 443
            .|.:..|.::|::....||:|..:          |...|   |....|...|..:|.:|||:
plant   115 IVTSAADKQVRYSKILESGQVETSLLGKHQGPVHKLAVEPGSPFSFYTCGEDGAVKHFDLRTRVA 179

  Fly   444 ---IACIETKFAGSSCNDLVTTDSL-------GSTIISGHYDKKIRFWDIRTEK--------QAD 490
               ..|.|.||     |.:|...::       |...::| .|:..|.:|||:.:        |..
plant   180 TNLFTCKEAKF-----NLVVYLHAIAVDPRNPGLLAVAG-MDEYARVYDIRSYRSEGWYNFTQPI 238

  Fly   491 DVLMPAK--------ITSLDLSKDCNYLICSVRDDTIKLL------------------DLRKNQV 529
            |...|..        ||.|..| |.:.|:.|..|:.|.|.                  :....||
plant   239 DHFCPGHLIGDDHVGITGLAFS-DQSELLASYSDEFIYLFTPDMGLGPTPYPSSTKTEERMTPQV 302

  Fly   530 ISTFTNEH-------FKISCDFARASFNSSGLKIACGSADGAIYIW-NVNGFLEATLKGHSTAVN 586
            ....||..       |...|::           :..||..|.|:|| ..:|.|...::.....||
plant   303 YKEHTNRETVKGVNFFGPKCEY-----------VVSGSDCGRIFIWRKKDGELLRAMEADRHVVN 356

  Fly   587 AVSWSPNNNMLASVG 601
            .:...|:..::.|.|
plant   357 CIESHPHMPLMCSSG 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atg16	NP_001138124.2	ATG16	11..197	CDD:285778
		SynN	120..229	CDD:294095
		WD40	322..605	CDD:238121	78/348 (22%)
		WD40 repeat	331..368	CDD:293791	10/36 (28%)
		WD40	<341..612	CDD:225201	76/329 (23%)
		WD40 repeat	374..410	CDD:293791	8/35 (23%)
		WD40 repeat	415..453	CDD:293791	14/56 (25%)
		WD40 repeat	461..491	CDD:293791	8/44 (18%)
		WD40 repeat	498..536	CDD:293791	13/55 (24%)
		WD40 repeat	544..579	CDD:293791	8/35 (23%)
		WD40 repeat	585..609	CDD:293791	5/17 (29%)
AT4G38480	NP_568042.1	WD40	<1..95	CDD:225201	26/104 (25%)
		WD40	51..379	CDD:392136	78/348 (22%)
		WD40 repeat	60..96	CDD:293791	11/39 (28%)
		WD40 repeat	102..141	CDD:293791	10/42 (24%)
		WD40 repeat	147..186	CDD:293791	9/38 (24%)
		WD40 repeat	194..247	CDD:293791	11/53 (21%)
		WD40 repeat	254..304	CDD:293791	12/50 (24%)
		WD40 repeat	355..379	CDD:293791	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910