DRSC/TRiP Functional Genomics Resources

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Protein Alignment Atg16 and copb2

DIOPT Version :9

Sequence 1:NP_001138124.2 Gene:Atg16 / 326115 FlyBaseID:FBgn0039705 Length:612 Species:Drosophila melanogaster
Sequence 2:NP_001001940.1 Gene:copb2 / 114454 ZFINID:ZDB-GENE-010724-7 Length:934 Species:Danio rerio


Alignment Length:260 Identity:59/260 - (22%)
Similarity:101/260 - (38%) Gaps:34/260 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   322 FEAHENESHAVRWSPVE-RMVATGGADRKVKLWDIGKNSTEPRAVLSGSSAGINSVDFDSTG--A 383
            ||.|.:....:..:|.: ...|:...||.:|:|.:|  |:.|...|.|...|:|.:|:.|.|  .
Zfish   138 FEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLG--SSSPNFTLEGHDKGVNCIDYYSGGDKP 200

  Fly   384 YILGTSNDYGARVWTVMDNRLRHTLTGHSGKVMAAKYVQEPIKVVTGSHDRTLKIWDLRSIACIE 448
            |::..::|...::|...:.....||.||:..|....:..|...::|||.|.|::||...:.....
Zfish   201 YLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCVNFHPELPIIITGSEDGTVRIWHSSTYRLES 265

  Fly   449 TKFAGSS---CNDLVTTDSLGSTIISGHYDKKIRFWDIRTEKQADDVLMPAKITSLDLSKDCNYL 510
            |...|..   |    .:...||..::..||:......:..|:.|             :|.|.|..
Zfish   266 TLNYGMERVWC----VSGLRGSNSVALGYDEGSIIIKLGREEPA-------------MSMDTNGK 313

  Fly   511 ICSVRDDTIKLLDLRKNQVISTFTNEHFKI------SCDF--ARASFNSSG-LKIACGSADGAIY 566
            |...:...|:..:|:..........|...:      ||:.  .....|.:| ..:.||..:..||
Zfish   314 IIWAKHSEIQQANLKAMGDAEIKDGERLPLAVKDMGSCEIYPQTIQHNPNGRFVVVCGDGEYIIY 378

  Fly   567  566
            Zfish   379  378

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Atg16NP_001138124.2 ATG16 11..197 CDD:285778
SynN 120..229 CDD:294095
WD40 322..605 CDD:238121 59/260 (23%)
WD40 repeat 331..368 CDD:293791 10/37 (27%)
WD40 <341..612 CDD:225201 55/240 (23%)
WD40 repeat 374..410 CDD:293791 9/37 (24%)
WD40 repeat 415..453 CDD:293791 10/37 (27%)
WD40 repeat 461..491 CDD:293791 6/29 (21%)
WD40 repeat 498..536 CDD:293791 6/37 (16%)
WD40 repeat 544..579 CDD:293791 6/26 (23%)
WD40 repeat 585..609 CDD:293791
copb2NP_001001940.1 WD40 8..297 CDD:238121 42/164 (26%)
WD40 repeat 19..55 CDD:293791
WD40 24..428 CDD:225201 59/260 (23%)
WD40 repeat 103..140 CDD:293791 1/1 (100%)
WD40 repeat 145..182 CDD:293791 9/38 (24%)
WD40 repeat 189..226 CDD:293791 8/36 (22%)
WD40 repeat 232..262 CDD:293791 9/29 (31%)
Coatomer_WDAD 320..763 CDD:281977 11/59 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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