DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaNE3 and P4H2

DIOPT Version :9

Sequence 1:	NP_651814.1	Gene:	PH4alphaNE3 / 326114	FlyBaseID:	FBgn0051017	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_566279.1	Gene:	P4H2 / 819804	AraportID:	AT3G06300	Length:	299	Species:	Arabidopsis thaliana

Alignment Length:	227	Identity:	63/227 - (27%)
Similarity:	110/227 - (48%)	Gaps:	34/227 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   281 CRYNSTTSAFLILAPLKMEEISLEPHIVVYHDILPDKDIQQLITLAEPLLKPTEMFDDNKNEAR- 344
            |..:|.:|   |:.|.|::::|.:|...||...|.|.:...||:||:..|:.:.:.|::..|::
plant    24 CLISSPSS---IINPSKVKQVSSKPRAFVYEGFLTDLECDHLISLAKENLQRSAVADNDNGESQV 85

  Fly   345 SSYRTPLG-------GPLLDSLTQRMRDITGLQIRQGNPINIIKYGFGAPYTNYYDFFKKRNSES 402
            |..||..|       .|::..:..::...|.|....|..:.:::|..|..|..::|:|..:.:.:
plant    86 SDVRTSSGTFISKGKDPIVSGIEDKLSTWTFLPKENGEDLQVLRYEHGQKYDAHFDYFHDKVNIA 150

  Fly   403 KGFGDRMATFMFYLNDAPYGGATVFP---------------------RLNVKVPAERGKVLFWYN 446
            :| |.|:||.:.||::...||.||||                     :..:.|..::|..|.::|
plant   151 RG-GHRIATVLLYLSNVTKGGETVFPDAQEFSRRSLSENKDDLSDCAKKGIAVKPKKGNALLFFN 214

  Fly   447 LNGDTHDMEPTTMHAACPVFHGSKWVMTAWIH 478
            |..|... :|.::|..|||..|.||..|.|||
plant   215 LQQDAIP-DPFSLHGGCPVIEGEKWSATKWIH 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE3	NP_651814.1	P4Ha_N	25..149	CDD:285528
PH4alphaNE3	NP_651814.1	P4Hc	316..478	CDD:214780	50/190 (26%)
P4H2	NP_566279.1	P4Hc	55..245	CDD:214780	50/191 (26%)
P4H2	NP_566279.1	ShKT	259..299	CDD:214586
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1438683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.930