DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaNE3 and AT-P4H-1

DIOPT Version :9

Sequence 1:	NP_651814.1	Gene:	PH4alphaNE3 / 326114	FlyBaseID:	FBgn0051017	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_181836.1	Gene:	AT-P4H-1 / 818910	AraportID:	AT2G43080	Length:	283	Species:	Arabidopsis thaliana

Alignment Length:	222	Identity:	59/222 - (26%)
Similarity:	101/222 - (45%)	Gaps:	31/222 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   284 NSTTSAFLILAPLKMEEISLEPHIVVYHDILPDKDIQQLITLAEPLLKPTEMFDDNKNE-ARSSY 347
            |...:..|.:..:|.|.:|..|.|:|.||.|..::.:.|..:|.|.|:.:.:.|....: .:|..
plant    63 NDKDAELLRIGNVKPEVVSWSPRIIVLHDFLSPEECEYLKAIARPRLQVSTVVDVKTGKGVKSDV 127

  Fly   348 RTPLG---------GPLLDSLTQRMRDITGLQIRQGNPINIIKYGFGAPYTNYYDFFKKRNSESK 403
            ||..|         .|::.::.:|:...:.:....|..|.:::|.....|..::|:|....:..:
plant   128 RTSSGMFLTHVERSYPIIQAIEKRIAVFSQVPAENGELIQVLRYEPQQFYKPHHDYFADTFNLKR 192

  Fly   404 GFGDRMATFMFYLNDAPYGGATVFP---------------RLNVKVPAERGKVLFW-YNLNGDTH 452
            | |.|:||.:.||.|...||.|.||               .::|| |.:...|||| ..|:|.:
plant   193 G-GQRVATMLMYLTDDVEGGETYFPLAGDGDCTCGGKIMKGISVK-PTKGDAVLFWSMGLDGQS- 254

  Fly   453 DMEPTTMHAACPVFHGSKWVMTAWIHE 479
              :|.::|..|.|..|.||..|.|:.:
plant   255 --DPRSIHGGCEVLSGEKWSATKWMRQ 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE3	NP_651814.1	P4Ha_N	25..149	CDD:285528
PH4alphaNE3	NP_651814.1	P4Hc	316..478	CDD:214780	48/187 (26%)
AT-P4H-1	NP_181836.1	PLN00052	80..281	CDD:177683	55/205 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H94894
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1438683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.930