DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaNE3 and P4H5

DIOPT Version :9

Sequence 1:	NP_651814.1	Gene:	PH4alphaNE3 / 326114	FlyBaseID:	FBgn0051017	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_179363.1	Gene:	P4H5 / 816281	AraportID:	AT2G17720	Length:	291	Species:	Arabidopsis thaliana

Alignment Length:	212	Identity:	64/212 - (30%)
Similarity:	108/212 - (50%)	Gaps:	31/212 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   298 MEEISLEPHIVVYHDILPDKDIQQLITLAEPLLKPTEMFDDNKNEARSS-YRTPLG-------GP 354
            :|.||.||..||||:.|.:::.:.||:||:|.:..:.:.|:....::.| .||..|       ..
plant    80 VEVISWEPRAVVYHNFLTNEECEHLISLAKPSMVKSTVVDEKTGGSKDSRVRTSSGTFLRRGHDE 144

  Fly   355 LLDSLTQRMRDITGLQIRQGNPINIIKYGFGAPYTNYYDFFKKRNSESKGFGDRMATFMFYLNDA 419
            :::.:.:|:.|.|.:.:..|..:.::.|..|..|..:||:|....:...| |.|:||.:.||:|.
plant   145 VVEVIEKRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFLDEFNTKNG-GQRIATVLMYLSDV 208

  Fly   420 PYGGATVFP--RLNVK------------------VPAERGKVLFWYNLNGDTHDMEPTTMHAACP 464
            ..||.||||  |.|:.                  :|.:|..:||| |:..|. .::|:::|..||
plant   209 DDGGETVFPAARGNISAVPWWNELSKCGKEGLSVLPKKRDALLFW-NMRPDA-SLDPSSLHGGCP 271

  Fly   465 VFHGSKWVMTAWIHEYD 481
            |..|:||..|.|.|.::
plant   272 VVKGNKWSSTKWFHVHE 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE3	NP_651814.1	P4Ha_N	25..149	CDD:285528
PH4alphaNE3	NP_651814.1	P4Hc	316..478	CDD:214780	53/189 (28%)
P4H5	NP_179363.1	PLN00052	75..290	CDD:177683	64/212 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1438683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.930