Protein Alignment PH4alphaNE3 and p4ha2

DIOPT Version :9

• Sequence 1: NP_651814.1
• Gene: PH4alphaNE3 / 326114
• FlyBaseID: FBgn0051017
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: XP_012814344.2
• Gene: p4ha2 / 493342
• XenbaseID: XB-GENE-957618
• Length: 537
• Species: Xenopus tropicalis
• Alignment Length: 516
• Identity: 145/516 - (28%)
• Similarity: 239/516 - (46%)
• Gaps: 57/516 - (11%)

  Fly    11 WESRQEFLDTESAKMDLMQLDVELIDNLMNYAEKIDEKASQLKRLAQELRQPLHSAKGREEEYLG 75
            ||.:.|...:.....||:..:.:|:.:|..|..:.:|:.|::||.|.|:.:....:....|.|||
 Frog    17 WEVQTEVFTSTGQMTDLIFRERDLLQSLKEYIREEEERLSKIKRWASEVDELSSRSTADPEGYLG 81

  Fly    76 NPLHSFPLIRHMYQDWRYLEEFMKKPVGEEEIQFLRRKLPELPWQVDTEEASVSIFRIAETYGMM 140
            :|::::.|::....||..||..:.:...:..|.....:....|.:.|...|:.::.||.:||.:.
 Frog    82 HPVNAYKLVKRFNTDWSSLENLVLQDSAKGFIANFTFQREYFPTEEDETGAARALMRIQDTYKLD 146

  Fly   141 PWDMANGLIDNVRFNSTLPALDCFEVAKMYFKWGYFKQALQWITISKARMKEEYSGVYEVLGMNR 205
            |..:|.|.:....:.|:|.|.|.|.:.|:.:..|.:...:.|:..:..:|.|....|     :|:
 Frog   147 PDVIAKGKLPGTNYISSLSADDSFGMGKIAYHDGDYYHTVLWMQQALKQMDEGEDAV-----VNK 206

  Fly   206 QDV----------------ALLQARCLVELD-RRDEAHEVLLDQPDLADNSISLLDQFKANPYEA 253
            .||                ||...:.|:.|| ..|.|...|.....:.:...:.|.|.::...|:
 Frog   207 VDVLDYLSYTVFQLGDVPRALELTKRLLALDPNHDRAVNNLKYFEKMQEKQKAELKQNESTNTES 271

  Fly   254 IDSSPKL----------GEGYKRLCR-SSFSPNP---SKLHCRY-NSTTSAFLILAPLKMEEISL 303
            ....|.:          .:.|:.||| .....||   .:|.||| |...|.:|||:|:|:|:...
 Frog   272 ATRQPGVYSRPLDYLPERDVYEALCRGEGVKMNPRRQRRLFCRYHNGNRSPYLILSPVKVEDEWD 336

  Fly   304 EPHIVVYHDILPDKDIQQLITLAEPLLKPTEMFDD--------NKNEARSSYRTPLGGPLLDSLT 360
            .|.||.|.:.|.|::|.::..||:|.|....:.|.        |...::|::......|::..:.
 Frog   337 SPRIVRYLNALSDEEIAKIKELAKPKLARATVRDPKTGVLSVANYRVSKSAWLEENDDPVIARVN 401

  Fly   361 QRMRDITGLQIRQGNPINIIKYGFGAPYTNYYDFFKKRNSE---SKGFGDRMATFMFYLNDAPYG 422
            .||:.||||.:.....:.:..||.|..|..::||.:|...:   ..|.|:|:|||:.|::|...|
 Frog   402 LRMQAITGLTVDTAELLQVANYGMGGQYEPHFDFSRKDEPDVFKRLGTGNRVATFLNYMSDVEAG 466

  Fly   423 GATVFPRLNVKVPAERGKVLFWYNL----NGDTHDMEPTTMHAACPVFHGSKWVMTAWIHE 479
            ||||||.....:..::|..:|||||    .||..     |.||||||..|||||...|.||
 Frog   467 GATVFPDFGAAIWPKKGTAVFWYNLFRSGEGDYR-----TRHAACPVLVGSKWVSNKWFHE 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE3	NP_651814.1	P4Ha_N	25..149	CDD:285528	32/123 (26%)
		P4Hc	316..478	CDD:214780	59/176 (34%)
p4ha2	XP_012814344.2	P4Ha_N	27..113	CDD:400573	21/85 (25%)
		TPR repeat	166..201	CDD:276809	8/34 (24%)
		TPR repeat	206..236	CDD:276809	5/29 (17%)
		P4Hc	348..521	CDD:214780	59/177 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010